Stretchable Material for Microfluidic Applications

Fouillet, Yves; Parent, Charlotte; Gropplero, Giacomo; Davoust, Laurent; Achard, Jean Luc; Revol-Cavalier, Frédéric; Verplanck, Nicolas

doi:10.3390/proceedings1040501

Cited by 15 publications

(12 citation statements)

References 4 publications

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“…First, the elastomer was highly stretchable: It had a much smaller elastic modulus (i.e., 50 kPa; Fig. 3C ) compared to the pH-responsive hydrogel (i.e., 800 kPa) and can stretch up to 980% of its original length without breaking ( 33 ). We found from scanning electron microscopy (SEM) that the thickness of the coating of elastomer was <1 μm ( Fig.…”

Section: Resultsmentioning

confidence: 99%

Performing calculus: Asymmetric adaptive stimuli-responsive material for derivative control

et al. 2021

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Materials (e.g., brick or wood) are generally perceived as unintelligent. Even the highly researched “smart” materials are only capable of extremely primitive analytical functions (e.g., simple logical operations). Here, a material is shown to have the ability to perform (i.e., without a computer), an advanced mathematical operation in calculus: the temporal derivative. It consists of a stimuli-responsive material coated asymmetrically with an adaptive impermeable layer. Its ability to analyze the derivative is shown by experiments, numerical modeling, and theory (i.e., scaling between derivative and response). This class of freestanding stimuli-responsive materials is demonstrated to serve effectively as a derivative controller for controlled delivery and self-regulation. Its fast response realizes the same designed functionality and efficiency as complex industrial derivative controllers widely used in manufacturing. These results illustrate the possibility to associate specifically designed materials directly with higher concepts of mathematics for the development of “intelligent” material-based systems.

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Section: Resultsmentioning

confidence: 99%

Performing calculus: Asymmetric adaptive stimuli-responsive material for derivative control

et al. 2021

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“…Since the fluidic capacitor is a deformable unit, in order to investigate the effect of the material stiffness on the resulting droplet deformation, two materials typically used in microfluidics and characterized by different elastic moduli are considered: Sylgard 184 PDMS and Ecoflex 00–50. The former is prepared by double replica molding using a 20:1 base/curing agent w/w formulation to achieve higher elasticity than conventional PDMS (elastic modulus = 0.50 MPa);26 differently, the latter is prepared by replica molding following the manufacturer's protocol (elastic modulus = 0.20 MPa) 27,28. Finally, the unmolded structures are bonded on a flat surface of the same material by oxygen plasma.…”

Section: Resultsmentioning

confidence: 99%

“…The former is prepared by double replica molding using a 20:1 base/curing agent w/w formulation to achieve higher elasticity than conventional PDMS (elastic modulus = 0.50 MPa); [26] differently, the latter is prepared by replica molding following the manufacturer's protocol (elastic modulus = 0.20 MPa). [27,28] Finally, the unmolded structures are bonded on a flat surface of the same material by oxygen plasma.…”

Section: Microfluidic Devices' Fabricationmentioning

confidence: 99%

Development of a Droplet Microfluidics Device Based on Integrated Soft Magnets and Fluidic Capacitor for Passive Extraction and Redispersion of Functionalized Magnetic Particles

Serra

Gontran

Hajji

et al. 2020

Adv Materials Technologies

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Based on a recent droplet microfluidic device for target molecules' extraction, purification, and redispersion, here an original fluidic control system is proposed to improve the device versatility and usability. This approach relies on the coupling of functionalized magnetic particles handling by integrated soft magnets and a passive droplet splitting control at a channel junction. To reach the high standards required for bioassays' implementation, this device integrates a pressure‐driven variable volume component, acting as a fluidic capacitor, which allows a passive and controlled self‐triggered droplet fingering in a dead‐end channel. The working principle is described, and the modeling of the induced fingering phenomenon by an electric analogy is presented. Then, the achieved finger length is characterized as a function of geometrical and material properties of the fluidic capacitor. The complete device configuration guarantees extraction and purification efficiencies higher than 97% and 95%, respectively, showing high‐throughput particles handling between droplets with a passive droplet splitting control. Finally, this technology is successfully applied to gene expression study for cancer diagnosis by performing magnetic particle–based messenger RNA (mRNA) extraction followed by reverse transcription (RT) and quantitative polymerase chain reaction (RT‐qPCR) analysis.

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“…Taking a step further to real applications, we have integrated the RFID stretchable sensor into a soft chamber which is made of silicone materials with pneumatic channels based on the structure described in [23] since it is compatible with soft lithography [24] technology. In the fabricated soft chamber, a series of pneumatic channels were embedded in an extensible Ecoflex layer and bonded to a relatively less extensible PDMS layer (Young's Modulus of Ecoflex is 69 kPa [13] whereas PDMS is 0.8-3MPa [25]). When compressed air is injected into the chamber, the chamber inflates like balloons.…”

Section: Resultsmentioning

confidence: 99%

Soft Wireless Battery-Free UHF RFID Stretchable Sensor Based on Microfluidic Technology

Pan¹,

Teng²,

Leng³

et al. 2019

IEEE J. Radio Freq. Identif.

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Stretchable microfluidic sensors have recently been developed and employed in many sensing applications. However, they are still in their early stage of development and facing considerable challenges, such as practical system integration due to the limitation of costs, wired connections and sensitivity. In this work, we present a compact soft wireless battery-free RFID stretchable sensor based on microfluidic technology. The proposed RFID sensor has high sensitivity and is able to be stretched to 160% of its original size. Moreover, the sensor is completely wireless powered and battery-free. It can be fully embedded into sensor carriers such as robots to eliminate wires, reduce the weight and increase the agility. Difference to known received signal strength indicator (RSSI) techniques for RFID sensing monitoring, resonance frequency shift is used in this work, significantly increasing the measurement accuracy, usefulness and reliability for many practical applications.

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Stretchable Material for Microfluidic Applications

Cited by 15 publications

References 4 publications

Performing calculus: Asymmetric adaptive stimuli-responsive material for derivative control

Performing calculus: Asymmetric adaptive stimuli-responsive material for derivative control

Development of a Droplet Microfluidics Device Based on Integrated Soft Magnets and Fluidic Capacitor for Passive Extraction and Redispersion of Functionalized Magnetic Particles

Soft Wireless Battery-Free UHF RFID Stretchable Sensor Based on Microfluidic Technology

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