Striatal cells containing aromatic l-amino acid decarboxylase: an immunohistochemical comparison with other classes of striatal neurons

Morphology and distribution of dopaminergic neurons intrinsic to the human striatum

“…In addition to the SNc, putative DA cells have been visualized in the striatum, which is the major target site of the SNc. Neurons positive for tyrosine hydroxylase (TH), the rate-limiting enzyme in the biosynthesis of catecholamines, have been detected in the striatum of mice (Baker et al, 2003), rats (Tashiro et al, 1989;Mura et al, 1995Mura et al, , 2000Meredith et al, 1999), monkeys (Dubach et al, 1987;Betarbet et al, 1997;Palfi et al, 2002) and humans (Cossette et al, 1999(Cossette et al, , 2003Porritt et al, 2000).…”

Degeneration of dopaminergic neurons triggers an expression of individual enzymes of dopamine synthesis in non-dopaminergic neurons of the arcuate nucleus in adult rats

“…Noteworthy, both types of monoenzymatic neurons appear in the striatum following pharmacologically induced degeneration of dopaminergic neurons in the substantia nigra (Mura et al, 1995(Mura et al, , 2000Meredith et al, 1999;LopezReal et al, 2003). Some authors succeeded in detecting occasional monoenzymatic neurons in the striatum even in intact adult mammals (Dubach et al, 1987;Ikemoto et al, 1997).…”

Are D-Neurons and Trace Amine-Associated Receptor, Type 1 Involved in Mesolimbic Dopamine Hyperactivity of Schizophrenia?

“…In this usage, the classification term "D" means decarboxylation. In rodents [13,16,17], a small number of D-cells in the striatum were rostrally described and confirmed to be neurons by electron-microscopic observation [13].…”