The geology, the geophysics, and other components of the solid earth system have much to contribute to our understanding of the Mediterranean region, from the Tethys paleo-environment to the present-day plate tectonic boundary. Launching a special collection with new and revised research contributions on the Tethyan belt (Mediterranean to Middle East), addressing subduction and mantle convection, volcanism, and fluid circulation, structural geology and active tectonics, dynamic topography, and geomorphology is a challenge. Attempting to embrace all these topics may seem ambitious, but this effort embodies the spirit of Renato Funiciello, the Mediterranean and Italian geologist who crossed the sea beforehand and spread the seeds of modern tectonics and geodynamics. This special section is dedicated to him. This collection encompasses a broad spectrum of topics including regional and structural geology, deep-seated metamorphism and core complexes, active deformation, and tectonics, using diverse approaches, such as high-resolution topographic and GPS data, paleomagnetic and magnetic measurements, seismic tomography, isotopic dating, and analog/numerical modeling in either strike-slip extensional and contractional tectonic systems.