Strong, tough, and elastic poly(vinyl alcohol)/polyacrylamide DN hydrogels based on the Hofmeister effect for articular cartilage replacement

Abstract

Traditional hydrogels are usually weak and brittle, which limit their application as articular cartilage replacement because the nature cartilage is generally strong, tough, and elastic. Therefore, it is highly desired...

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy

“…These hydroxyl groups contribute to its excellent water solubility and ability to form hydrogen bonds, endowing PVA hydrogels with good biocompatibility and mechanical properties. They find wide applications in the biomedical field, such as wound dressings, artificial cartilage, and drug delivery systems [ [153] , [154] , [155] ]. Constructing a double network structure is a common method to enhance the toughness and strength of PVA-based hydrogels [ 156 ].…”