“…For example, it is assumed that H3K36me3 is linked to DNA repair in transcriptionally active regions, and it is thought the DNA repair processes involve drastic structural alterations of chromatin, namely complex of DNA and histone proteins, induced by the post-translational modifications of histones [ 21 , 22 , 26 , 27 ]. However, experimental and theoretical studies on the structural changes of histone, induced by modifications or DNA damage repair processes, are not so abundant [ 17 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 ]. To precisely understand the mechanism of chromatin structural remodeling, cyclopedic studies of modification-induced structural changes of histones would be necessary.…”