Structural and photophysical properties of novel dual fluorescent compounds, 1‐aryl‐substituted 6‐methoxy‐4‐quinolones

Abstract

Dual fluorescent compounds are useful platforms for the development of ratiometric probes and sensors. We have developed a new series of dual fluorescent compounds, 1-aryl-substituted 6-methoxy-4-quinolones, and investigated their structural and photophysical properties. The X-ray crystallographic analysis and ab initio quantum chemical calculations revealed that the developed compounds exhibited 60-75 degrees twisted structures. The dual fluorescence of the compounds were observed in polar solvents, and the ratiometric fluorescence responses to alterations in the acidity and temperature were obtained.

Spectroscopic characterization, photoinduced processes and cytotoxic properties of substitutedN-ethyl selenadiazoloquinolones

“…[32,[35][36][37][38] Figure 1b shows the fluorescence emission spectra of the studied selenadiazoloquinolones in DMSO. Excitation at 410 nm was performed in all cases.…”

Synthesis, structure–activity relationship and molecular docking of cyclohexenone based analogous as potent non-nucleoside reverse-transcriptase inhibitors

“…Cyclohexenone carboxylates have known to possess anti-cancer [28], anti-HIV [29][30][31], anti-fungal [32], anti-tumor [33,34], anticonvulsant [21,35] and antitubercular [36] activity. A series of novel cyclohexenone derivatives have been synthesized, which are used in the treatment of neurological disorders [37] as well as efficient fluorescent probes for biomembranes [38][39][40].…”

Unprecedented Synthesis of 2‐Aminochromones and 2‐Aminoquinolones through an Electrophilic C–Cyanation and 6‐exo‐dig Cyclization Cascade with the Intermediary of β‐Ketonitriles

“…All these compounds exhibit moderate to high cytotoxic activity. Fluorescent quinolones, including some quinolones fused with other heterocycles,, are potentially used for these applications, have recently been reported. Therefore synthesis of these classes of compounds have been active field of research.…”