Handbook of Space Pharmaceuticals 2020
DOI: 10.1007/978-3-319-50909-9_48-1
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Structural Brain Changes Associated with Space

Abstract: Space flight occurs in an extremely hostile environment, one for which man is inherently poorly adapted. As the duration of flight increases, more clinical syndromes and cerebral structural changes are being described, suggesting a direct relationship to time of exposure. There is now emerging evidence for involvement of the neuro-ocular system, cerebrospinal fluid, gray matter, and white matter. A definitive pathophysiological mechanism remains elusive with investigation hampered by the limited number of stud… Show more

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