Structural changes and impairment of function associated with freezing and thawing in muscle, nerve, and leucocytes

Menz, Leo J.

doi:10.1016/0011-2240(71)90102-7

Cited by 34 publications

(11 citation statements)

References 16 publications

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“…The least amount of changes occur between −5 and −10°C, however below −15°C results in ruptures in the myelin and separation of the lamellae [27][28].…”

Section: Appendix 1: Optical Behavior Of Nerve Tissue After Freezing mentioning

confidence: 99%

Evaluation of collimated polarized light imaging for real-time intraoperative selective nerve identification in the human hand

Chin¹,

Engelsman²,

Chin³

et al. 2017

Biomed. Opt. Express

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Abstract:Intraoperative peripheral nerve lesions are common complications due to misidentification and limitations of surgical nerve identification. This study validates a realtime non-invasive intraoperative method of nerve identification. Long working distance collimated polarized light imaging (CPLi) was used to identify peripheral radial nerve branches in a human cadaver hand by their nerve specific anisotropic optical reflection. Seven ex situ and six in situ samples were examined for nerves, resulting after histological validation, in a 100% positive correct score (CPLi) versus 77% (surgeon). Nerves were visible during a clinical in vivo observation using CPLi. Therefore CPLi is a promising technique for intraoperative nerve identification. for high resolution fat-suppressed imaging of the brachial and lumbosacral plexuses," Eur.

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“…The least amount of changes occur between −5 and −10°C, however below −15°C results in ruptures in the myelin and separation of the lamellae [27][28].…”

Section: Appendix 1: Optical Behavior Of Nerve Tissue After Freezing mentioning

confidence: 99%

Evaluation of collimated polarized light imaging for real-time intraoperative selective nerve identification in the human hand

Chin¹,

Engelsman²,

Chin³

et al. 2017

Biomed. Opt. Express

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“…Most of the damaging effect occurred in the underlying myoflbers where a freeze-thaw-rigor injury took place (13,17,19). Most of the damaging effect occurred in the underlying myoflbers where a freeze-thaw-rigor injury took place (13,17,19).…”

Section: Discussionmentioning

confidence: 99%

“…Work with cold injury to tongue and other muscles has shown that without destruction of overlying epithelium, muscle undergoes localised damage followed by rapid regeneration (13,17,19). We describe here progressive changes after direct cold injury to the outer surface of the *) This work was supported by the Muscular Dystrophy Association of America.…”

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confidence: 97%

Myofibroblasts in subepicardium after local cold injury

Yarom¹,

Havivi²

1979

Basic Res Cardiol

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Rat hearts were exposed and injured locally by direct cryoapplication. The hearts were examined 2, 4, 20 and 48 hours, 7 and 12 days later. In the first 48 hours mast cell and polymorphonuclear (mainly eosinophilic) granulocyte infiltration was followed by proliferation of mononuclear phagocytic and fibroblastic cells and new capillaries. The underlying muscle showed freeze-thaw-rigor damage, segmental intramyofiber necrosis, phagocytosis and focal regeneration. After 7 days numerous myofibroblasts appeared and they were intimately related to myofibers undergoing degeneration and repair. After 12 days there was increased fibrosis while mesothelial covering cells of the epicardium and myofibers returned to normal. It is suggested that amines released from mast cells are involved in the formation of myofibroblasts.

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“…There is also a paucity of good quality research in human tissue properties due to difficulties in obtaining post-mortem human subjects and the degradation in properties associated with the conditions the body is kept post-mortem prior to testing (Van Ee et al, 2000) and storage conditions (Menz, 1971;Lee & Pelker, 1985;Clavert et al, 2001). Consequently, very few studies presented are of human tissues (Chawla et al, 2009;Balaraman et al, 2012).…”

Section: Structure and Composition Of Organic Muscle Tissuementioning

confidence: 99%

Development of novel synthetic muscle tissues for sports impact surrogates

Payne

Mitchell

Bibb

et al. 2015

Journal of the Mechanical Behavior of Biomedical Materials

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Impact injuries are commonplace in sport and often lead to performance detriment and debilitation. Personal Protective Equipment (PPE) is prescribed as a mandatory requirement in most sports where these impacts are likely to occur, though the methods of governance and evaluation criteria often do not accurately represent sports specific injury scenarios. One of the key shortcomings of such safety test standards is the human surrogate to which the PPE is affixed; this typically embodies unrepresentative geometries, masses, stiffness and levels of constraint when compared to humans.A key aspect of any human surrogate element is the simulant material used. Most previous sports specific surrogates tend to use off-the-shelf silicone blends to represent all the soft tissue structures within the human limb segment or organ; this approach potentially neglects important human response phenomena caused by the different tissue structures.This study presents an investigation into the use of bespoke additive cure Polydimethysiloxane (PDMS) silicone blends to match the reported mechanical properties of human relaxed and contracted skeletal muscle tissues. The silicone simulants have been tested in uniaxial compression through a range of strain rates and fit with a range of constitutive hyperelastic models (Mooney Rivlin, Ogden and Neo Hookean) and a viscoelastic Prony series.

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Structural changes and impairment of function associated with freezing and thawing in muscle, nerve, and leucocytes

Cited by 34 publications

References 16 publications

Evaluation of collimated polarized light imaging for real-time intraoperative selective nerve identification in the human hand

Evaluation of collimated polarized light imaging for real-time intraoperative selective nerve identification in the human hand

Myofibroblasts in subepicardium after local cold injury

Development of novel synthetic muscle tissues for sports impact surrogates

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