Structural characterization and antioxidant activities of a novel polysaccharide fraction from the fruiting bodies of Craterellus cornucopioides

Yang, Weiwei; Wang, Liming; Gong, Lili; Lu, Yongming; Pan, Wen-Juan; Wang, Ya; Zhang, Wenna; Chen, Yan

doi:10.1016/j.ijbiomac.2018.05.212

Cited by 42 publications

(38 citation statements)

References 39 publications

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“…Guo et al 4 isolated two new illudane sesquiterpenoids, craterellins D and E, and one new menthane monoterpene, 4-hydroxy-4-isopropenyl-cyclohexanemethanol acetate, from C. cornucopioides and evaluated their cytotoxic activities. Similarly, Yang et al 5 isolated a novel polysaccharide fraction from C. cornucopioides and explored its antioxidant activity.…”

mentioning

confidence: 99%

Craterellus cornucopioides Edible Mushroom as Source of Biologically Active Compounds

Kosanić

Ranković

Stanojković

et al. 2019

Natural Product Communications

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Here we determined the phenolic compounds and antioxidant, antimicrobial, genotoxic, and anticancer potential of edible mushrooms Craterellus cornucopioides. The phytochemical analysis was evaluated using high-performance liquid chromatography. Antioxidant activity was evaluated by free radical scavenging, superoxide anion scavenging, and reducing power. Craterellus cornucopioides extract had potent antioxidant activity. Further, the antimicrobial potential was determined by a microdilution method, where minimum inhibitory concentration values ranged from 0.1 to 10 mg/mL. Genotoxic potential was determined by cytokinesis block micronucleus test. The separate treatment did not show genotoxic effect, whereas the combined treatment with mitomycin C significantly reduced the micronuclei frequency in a dose-dependent manner. The highest concentration significantly reduced nuclear division index in comparison to untreated human peripheral blood lymphocytes, whereas in combined treatment, the extract did not significantly affect this parameter. Finally, the cytotoxic activity was tested using microculture tetrazolium test where measured IC 50 values ranged from 65.5 to 131.7 μg/mL.

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mentioning

confidence: 99%

Craterellus cornucopioides Edible Mushroom as Source of Biologically Active Compounds

Kosanić

Ranković

Stanojković

et al. 2019

Natural Product Communications

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“…Crude extracts of C. cibarius showed antioxidant [91], antimicrobial activity [92] and cytotoxic activities [93]. Yang et al [97] isolated a novel polysaccharide fraction from the fruiting bodies. The dominant linkage types were →3,6)-Manp (1→, T-Araf, →4,6)-Manp (1→, →5)-Araf (1→ and →3)-Araf (1→).…”

Section: Cantharellus Cibarius Frmentioning

confidence: 99%

“…Qi, et al described the chemical structures of six novel cerebrosides, named termitomycesphins A-F (see structures 90-95 in Figure 18), together with known cerebroside 96, and reported their neuritogenic activities [240,241]. Other two new cerebrosides, named termitomycesphins G (97) and H (98) were later isolated from this mushroom by the same research group [242]. Four new selinane-type sesquiterpenoids, named teucdiol C-F (see structures 99-102 in Figure 18), together with the known compounds teucdiol B (103) and epi-guaidiol A (104) were isolated by from a fermentation broth of T. albuminosus [243]; epi-guaidiol A (104) showed potent anti-acetylcholinesterase activity in a dose-dependent manner [243].…”

Section: Termitomyces Albuminosus (Berk) R Heimmentioning

confidence: 99%

“…Polysaccharide [97], Extract [91,93,105,106,108] Extract [105] Craterellin C (20) [98], Extract [93,105] Polysaccharide [94,96]. Extract (antimutagenic effects [105], antihyperglycemic [106] and anti-inflammatory activities [107,108])…”

Section: Thelephora Ganbajun M Zangmentioning

confidence: 99%

“…Termitomycesphins A-F (90-95) (neuritogenic activity [240,241]). Termitomycesphins G (97) and H (98) (neuritogenic activity [242]). epi-Guaidiol A (104) (anti-acetylcholinesterase activity [243]).…”

Section: Thelephora Ganbajun M Zangmentioning

confidence: 99%

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Bioactive Phytochemical Constituents of Wild Edible Mushrooms from Southeast Asia

et al. 2020

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Mushrooms have a long history of uses for their medicinal and nutritional properties. They have been consumed by people for thousands of years. Edible mushrooms are collected in the wild or cultivated worldwide. Recently, mushroom extracts and their secondary metabolites have acquired considerable attention due to their biological effects, which include antioxidant, antimicrobial, anti-cancer, anti-inflammatory, anti-obesity, and immunomodulatory activities. Thus, in addition to phytochemists, nutritionists and consumers are now deeply interested in the phytochemical constituents of mushrooms, which provide beneficial effects to humans in terms of health promotion and reduction of disease-related risks. In recent years, scientific reports on the nutritional, phytochemical and pharmacological properties of mushroom have been overwhelming. However, the bioactive compounds and biological properties of wild edible mushrooms growing in Southeast Asian countries have been rarely described. In this review, the bioactive compounds isolated from 25 selected wild edible mushrooms growing in Southeast Asia have been reviewed, together with their biological activities. Phytoconstituents with antioxidant and antimicrobial activities have been highlighted. Several evidences indicate that mushrooms are good sources for natural antioxidants and antimicrobial agents

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Optimization of ultrasound‐assisted aqueous two‐phase extraction of polysaccharides from seabuckthorn fruits using response methodology, physicochemical characterization and bioactivities

et al. 2022

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Background: Seabuckthorn fruits contains many active subtances, among them, the seabuckthorn polysaccharide is one of the main active ingredients, and exhibits diverse bioactivities. The extraction of polysaccharides from seabuckthorn fruits is the most important step for their wide applications. Ultrasound-assisted aqueous two-phase extraction (UA-ATPE) is a promising green method for extracting polysaccharides. Additionally, physicochemical characterization and antioxidant activities can evaluate the potential functions and applications in the food and medicine industries.Results: Based on the single-factor experiments, 20.70% (w/w) ammonium sulfate ((NH 4 ) 2 SO 4 ) and 27.56% (w/w) ethanol were determined as the suitable composition for aqueous two-phase. The optimum conditions of UA-ATPE obtained by response surface methodology were as follows: ultrasonic power (390 W), extraction time (41 min), liquid-to-material ratio (72: 1 mL/g), and the total yield of the polysaccharides reached 34.14 ± 0.10%, The molecular weights of the purified upper-phase seabuckthorn polysaccharide (PUSP) and the purified lower-phase seabuckthorn polysaccharide (PLSP) were 65 525 and 26 776 Da, respectively. PUSP and PLSP contained the same six monosaccharides (galacturonic acid, rhamnose, xylose, mannose, glucose and galactose), but with different molar ratios. Furthermore, PUSP and PLSP displayed certain viscoelastic property, had no triple helical structure, possessed different thermal stability, surface morphology and conformation in aqueous solution. PUSP and PLSP displayed strong antioxidant properties by the assays of scavenging ability of ABTS + •, the protection of DNA damage and erythrocyte hemolysis.Conclusion: UA-ATPE significantly increased the yield of seabuckthorn polysaccharides. PUSP and PLSP were different in many aspects, such as molar ratio, surface shape and antioxidant activities. Seabuckthornpolysaccharides possess great potential in medicine and functional foods.

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Structural characterization and antioxidant activities of a novel polysaccharide fraction from the fruiting bodies of Craterellus cornucopioides

Cited by 42 publications

References 39 publications

Craterellus cornucopioides Edible Mushroom as Source of Biologically Active Compounds

Craterellus cornucopioides Edible Mushroom as Source of Biologically Active Compounds

Bioactive Phytochemical Constituents of Wild Edible Mushrooms from Southeast Asia

Optimization of ultrasound‐assisted aqueous two‐phase extraction of polysaccharides from seabuckthorn fruits using response methodology, physicochemical characterization and bioactivities

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