Structural Characterization of a Novel Glucan from <i>Achatina fulica</i> and Its Antioxidant Activity

Liao, Ningbo; Chen, Shiguo; Ye, Xingqian; Zhong, Jianjun; Ye, Xuan; Yin, Xiaolei; Tian, Jenny

doi:10.1021/jf403896c

Cited by 51 publications

(21 citation statements)

References 32 publications

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“…Snail flesh extract has the potential to treat asthma and tuberculosis (Padmanabhan and Sujana ). The glucan extract from China white jade snail ( Achatina fulica ) and hot water extract of Isada krill have significant antioxidant activities, suggesting their potentials as dietary antioxidant (Liao and others ; Koomyart and others ). Ziconotide, a peptide found in marine cone snail, is approved for analgesic use (Cheung and others ).…”

Section: Nutritive Value and Health Benefits Of Shellfishmentioning

confidence: 99%

Shellfish: Nutritive Value, Health Benefits, and Consumer Safety

Venugopal

Gopakumar

2017

Comp Rev Food Sci Food Safe

267

156

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Shellfish is a major component of global seafood production. Specific items include shrimp, lobsters, oysters, mussels, scallops, clams, crabs, krill, crayfish, squid, cuttlefish, snails, abalone, and others. Shellfish, in general, contain appreciable quantities of digestible proteins, essential amino acids, bioactive peptides, long-chain polyunsaturated fatty acids, astaxanthin and other carotenoids, vitamin B 12 and other vitamins, minerals, including copper, zinc, inorganic phosphate, sodium, potassium, selenium, iodine, and also other nutrients, which offer a variety of health benefits to the consumer. Although shellfish are generally safe for consumption, their exposure to diverse habitats, the filter feeding nature of shellfish such as oysters, clams, and mussels, and unhealthy farming and handling practices may occasionally entail health risks because of possible presence of various hazards. These hazards include pathogenic organisms, parasites, biotoxins, industrial and environmental pollutants, heavy metals, process-related additives such as antibiotics and bisulfite, and also presence of allergy-causing compounds in their bodies. Most of the hazards can be addressed by appropriate preventive measures at various stages of harvesting, farming, processing, storage, distribution, and consumption. Furthermore, consumer safety of shellfish and other seafood items is strictly monitored by international, governmental, and local public health organizations. This article highlights the nutritional value and health benefits of shellfish items and points out the various control measures to safeguard consumer safety with respect to the products.

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Section: Nutritive Value and Health Benefits Of Shellfishmentioning

confidence: 99%

Shellfish: Nutritive Value, Health Benefits, and Consumer Safety

Venugopal

Gopakumar

2017

Comp Rev Food Sci Food Safe

267

156

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“…The NMR spectra of UP2 were shown in Fig 4 . According to previous studies [2, 4], the anomeric hydrogen chemical shifts of UP2 appear at δ 5.02, 4.95, 4.88 and 4.36 ppm. The heteronuclear single-quantum coherence (HSQC) spectrum of UP2 ( Fig 4C ), showed overlapping peaks around δ 4.88 ppm, indicating the presence of two different connections.…”

Section: Resultsmentioning

confidence: 54%

“…They are essential biological macromolecules, and are directly involved in life processes, exhibiting a variety of important biological functions [2, 7]. Furthemore, polysaccharides exhibit immune-enhancement, anti-tumor, antioxidant, and other biological activities [8–9].…”

Section: Introductionmentioning

confidence: 99%

Structure Elucidation of a Polysaccharide from Umbilicaria esculenta and Its Immunostimulatory Activity

Zhang

et al. 2016

PLoS ONE

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Umbilicaria esculenta has been used as a tonic food in China for several centuries owing to its pleasant flavor and health benefits. In this study, a water soluble polysaccharide, which we designated as UP2, with an average molecular weight of 3.33 × 105 Da, was isolated from U. esculenta cultivated in the Huangshan Mountain, by consecutive hot water extraction and anion-exchange chromatography. Gas chromatography analysis indicated that UP2 contained three kinds of monosaccharides, including mannose, glucose, and galactose at a molar ratio of 1.7:1.0:1.2. Linkage analysis of UP2 revealed the presence of (1 → 6)-linked glucosyl, (1 → 3,6)-linked glucosyl, t-linked galactosyl, (1 → 6)-linked galactosyl and (1 → 6)-linked mannosyl at a molar ratio of 0.7:4.6:4.1:2.2:9.1. Structural analysis determined that UP2 possessed a backbone consisting of (1 → 6)-linked β-D-glucopyranosyl and (1 → 6)-linked α-D-mannopyranosyl residues, which substituted at the O-3 position of (1 → 6)-linked β-D-glucopyranosyl residues by branches of (1 → 6)-linked α-D-galactopyranosyl and 1-linked β-D-galactopyranosyl residues. Immunostimulatory activity analysis showed that UP2 could stimulate the proliferation of RAW264.7 cells in a dose-dependent manner, and all the samples (20–500 μg/mL) were found to enhance nitric oxide production. The highest phagocytic activity of UP2 was observed at 200 μg/mL. Thus, UP2 may be a potential source of biological and pharmacological agents.

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“…The chemical composition analysis showed that PV-P2 and PV-P3 had higher content of protein and uronic acid, which might explain their stronger antioxidant activities as compared to PV-P1. The most pronounced hypothesis is that free radicals can abstract hydrogen atoms at all ring C H bonds on carbohydrate [32]. Therefore, the stronger antioxidant activities of PV-P2 and PV-P3 may be attributed to their higher levels of active hydroxyl groups, suggesting that the chemical compositions and structures were critical for the antioxidant capacities of P. vulgaris polysaccharides.…”

Section: Oracmentioning

confidence: 99%