The problem of low vibration energy collection efficiency in the environment is the focus of the current piezoelectric power generation technology. In order to improve the collection efficiency of vibration energy in the environment, a key technology of piezoelectric power generation is studied, which can collect the vibration energy of multiple directions in the environment. Firstly, the mathematical model of piezoelectric cantilever beam is established by using the basic theory of piezoelectric power generation technology, and the vibration mechanics analysis of the piezoelectric cantilever beam is carried out. Then, the finite element simulation of the piezoelectric cantilever beam is carried out by using ANSYS, and the natural frequency is consistent with the ambient vibration/environment frequency; finally, multi-directional piezoelectric power generation device is made, and the theoretical analysis and experimental test are carried out. The experimental results show that the key technology of multidirectional vibration piezoelectric power generation can effectively improve the collection efficiency of vibration energy in the environment.