Structural elucidation and immunostimulating property of a novel polysaccharide extracted from an edible mushroom Lentinus fusipes

Manna, Dilip K.; Maity, Prasenjit; Nandi, Ashis Kumar; Pattanayak, Manabendra; Panda, Bibhash C.; Mandal, Amit Kumar; Tripathy, Satyajit; Acharya, Krishnendu; Sahoo, Atish Kumar; Gupta, Nibha; Roy, Somnath; Islam, Syed S.

doi:10.1016/j.carbpol.2016.11.048

Cited by 38 publications

(14 citation statements)

References 38 publications

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“…The peaks at 2934 and 2937 cm −1 were assigned to aliphatic C–H stretching [25]. The absorption peaks around 1610, 1417, and 1070 cm −1 were assigned to bending vibration of C–OH and C–O stretching of ether and anti-symmetric stretching band of C–O–C groups, respectively [26]. The α and β conformations of the carbohydrate could be determined by the peak position of the terminal carbon in the 950–750 cm −1 region, where 870–840 cm −1 correspond to α configuration and β configuration belong to 890 cm −1 .…”

Section: Resultsmentioning

confidence: 99%

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Two Novel Polysaccharides in Psoralea corylifolia L and anti-A549 Lung Cancer Cells Activity In Vitro

Yin

Zhang

et al. 2019

Molecules

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Two novel water soluble heteroglycan (PCp-I and PCp-II) with anti-A549 lung cancer cells activity were isolated from Psoralea corylifolia L. Their average molecular weights were 2.721 × 104 and 2.850 × 104. PCp-I and PCp-II had the same monosaccharide composition, but their molar ratios were different. Based on methylation and NMR spectroscopy, the part structure of PCp-I was identified. The results of scanning electron microscope (SEM) showed that PCp-I had an irregular porous structure and PCp-II was flaky and irregularly curved. The results of thermogravimetry-differential scanning calorimetry (TG-DSC) showed that PCp-I and PCp-II had good thermal stability. Furthermore, PCp-I and PCp-II exhibited significant anti-A549 lung cancer cells activity (IC50 = 64.84 and 126.30 μM) in vitro.

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Section: Resultsmentioning

confidence: 99%

“…The proton and carbon shifts of residue E were fully identified according to 1 H- 1 H COSY and HSQC spectras (Table 5). The results were compared with previous data and methylation analysis, residue D was assigned as β-Glc p -(1→ [26,34].…”

Section: Resultsmentioning

confidence: 99%

Two Novel Polysaccharides in Psoralea corylifolia L and anti-A549 Lung Cancer Cells Activity In Vitro

Yin

Zhang

et al. 2019

Molecules

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“…The peak at 2980 indicated the C-H stretching vibration. 37 The peak at 1257 cm À1 was assigned to the O stretching vibration of the sulfate group. The stretching vibration peaks between 1136 and 1012 cm À1 suggested the presence of C-O-C and C-O-H, respectively; 38 the peak at 762 cm À1 indicated the presence of aglucans.…”

Section: Molecular Weight Of the Polysaccharidementioning

confidence: 99%

Chemical structure and biological properties of a polysaccharide isolated from Pleurotus sajor-caju

Seedevi

Ganesan

Mohan³

et al. 2019

RSC Adv.

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“…Manna and coworkers isolated a water soluble heteroglycan (Mw around 60 kDa) from the hot aqueous extract of Lentinus fusipes . The heteroglycan was found to be composed of D-galactose and D-glucose in the molar ratio of approximately 1 : 1, showing both in vitro splenocyte and macrophage activation and DPPH radical scavenging activity [ 77 ].…”

Section: Polysaccharides As Active Components Of Edible and Medicimentioning

confidence: 99%

Antifatigue Functions and Mechanisms of Edible and Medicinal Mushrooms

Geng

Siu

Wang

et al. 2017

BioMed Research International

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Fatigue is the symptom of tiredness caused by physical and/or psychological stresses. As fatigue is becoming a serious problem in the modern society affecting human health, work efficiency, and quality of life, effective antifatigue remedies other than pharmacological drugs or therapies are highly needed. Mushrooms have been widely used as health foods, because of their various bioactive constituents such as polysaccharides, proteins, vitamins, minerals, and dietary fiber. This paper reviews the major findings from previous studies on the antifatigue effects, the active components of mushrooms, and the possible mechanisms. Many studies have demonstrated the antifatigue effects of edible and medicinal mushrooms. These mushrooms probably mitigate human fatigue through effects on the functional systems, including the muscular, cardiovascular, hormone, and immune system. The bioactive constituents that contribute to the antifatigue effects of mushrooms may include polysaccharides, peptides, nucleosides, phenolic compounds, and triterpenoids. Further research is still needed to identify the active ingredients and to investigate their mechanism of action on the antifatigue effects. Since most previous studies have been carried out in animal models, more human trials should be performed to verify the antifatigue function of edible and medicinal mushrooms.

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Structural elucidation and immunostimulating property of a novel polysaccharide extracted from an edible mushroom Lentinus fusipes

Cited by 38 publications

References 38 publications

Two Novel Polysaccharides in Psoralea corylifolia L and anti-A549 Lung Cancer Cells Activity In Vitro

Two Novel Polysaccharides in Psoralea corylifolia L and anti-A549 Lung Cancer Cells Activity In Vitro

Chemical structure and biological properties of a polysaccharide isolated from Pleurotus sajor-caju

Antifatigue Functions and Mechanisms of Edible and Medicinal Mushrooms

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