Structural Evolution of Polyglycolide and Poly(glycolide-<i>co</i>-lactide) Fibers during the Heat-Setting Process

Dong, Zhimin; Miao, Yushuang; Cui, Huashuai; Huang, Qing; Li, Yiguo; Wang, Zongbao

doi:10.1021/acs.biomac.1c00449

Cited by 7 publications

(4 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As for PLA, PLGA-85, and PLGA-75, the amorphous region degraded first in the initial stage of degradation. During this process, the fractured molecular chains reorganized to form crystalline structures, commonly referred to as cleavage-induced crystallization and typically resulting in the formation of smaller-sized defective crystalline lamellae [12,40,41]. When the degradation of the amorphous region was complete, the crystalline region began to degrade, leading to a decrease in crystallinity.…”

Section: Changes In Thermal Properties and Aggregation Structurementioning

confidence: 99%

“…Biodegradable polymer materials are an important type of synthetic biomaterials that are widely used in medical fields such as trauma repair and tissue regeneration [12][13][14]. Among the developed biodegradable polymers, aliphatic polyesters have attracted attention due to their good melt processability, mechanical strength, and excellent degradability.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Degradation Behaviors of Polylactic Acid, Polyglycolic Acid, and Their Copolymer Films in Simulated Marine Environments

Chen,

Zhang,

et al. 2024

Polymers

View full text Add to dashboard Cite

Poly(lactic acid) (PLA) and poly(glycolic acid) (PGA) are extensively studied biodegradable polymers. However, the degradation behavior of their copolymer, poly(lactic-co-glycolic acid) (PLGA), in marine environments has not yet been confirmed. In this study, the changes in macroscopic and microscopic morphology, thermal properties, aggregation, and chemical structure of PLA, PGA, PLGA-85, and PLGA-75 (with 85% and 75% LA content) in simulated marine environments were investigated. Results revealed that degradation occurred through hydrolysis of ester bonds, and the degradation rate of PGA was faster than that of PLA. The amorphous region degraded preferentially over the crystalline region, leading to cleavage-induced crystallization and decreased thermal stability of PLA, PLGA-85, and PLGA-75. The crystal structures of PLGAs were similar to those of PLA, and the higher GA content, the faster was the degradation rate. This study provides a deeper understanding of the seawater degradation behaviors of PLA, PGA, and their copolymers, and provides guidance for the preparation of materials with controllable degradation performance.

show abstract

Section: Changes In Thermal Properties and Aggregation Structurementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Degradation Behaviors of Polylactic Acid, Polyglycolic Acid, and Their Copolymer Films in Simulated Marine Environments

Chen,

Zhang,

et al. 2024

Polymers

View full text Add to dashboard Cite

show abstract

“…22,23 In particular, a considerable amount of research has been elaborated that the higher molecular orientation showed the better mechanical properties in electrospun fibers from the mats level. 13,[24][25][26] In view of the practical application of fibers, in situ synchrotron radiation SAXS and WAXD testing techniques are introduced to explore the molecular chain orientation and crystallization of electrospun fibers by the uniaxial stretching, [27][28][29] which can effectively monitor the microstructure of the fibers under the action of heating and stretching.…”

Section: Introductionmentioning

confidence: 99%

Structural responses of electrospun PVDF fibers induced by specific stretching and ensuing heating

Li,

Zhang,

Han

et al. 2024

Journal of Polymer Science

View full text Add to dashboard Cite

Microstructure of electrospun fibers is often invoked to explain their properties but that is challenging to quantify properly. The electrospun PVDF fibers being rich in the β‐phase crystal due to excellent piezoelectric properties are promising energy‐harvesting materials for wearable and implantable applications. In this work, structural responses of electrospun PVDF fibers were investigated under the conditions of specific stretching at 25°C and ensuing heating from 25 to 170°C at strains of 5%, 10%, 20%, respectively, using the in situ WAXD with a thermos‐mechanical coupled equipment. In this process, the fiber morphology, and the crystal orientation, the crystal structure, the β‐phase content, as well as mechanical property of elctrospun PVDF fibers were studied. It is found that the specific stretching affects the β‐phase crystal more than ensuing heating when the heating temperature is lower than the melting temperature of the fibers. Moreover, after 20% stretching and ensuing heating to 150°C, the tensile strength of electrospun PVDF fibers membrane can rise to 12.8 MPa, which is more than three times that of the pristine fibers, which is attributed to the higher crystal orientation and β‐phase content, along with the alignment of the fibers. Therefore, structural responses of electrospun PVDF fibers induced by specific stretching and ensuing heating are propitious to explain and tailor their properties in practical applications, which also gives potential insights into other fibers.

show abstract

“…Our group systematically studied the structural evolution of PGA and P(GA -co- LA) fibers during the heat-setting process recently . In this study, on the basis of the previous work, the degradation performance of PGA and P(GA -co- LA) fibers at different heat-setting temperatures during degradation was deeply studied by WAXD, SAXS, and DSC measurements, as well as mechanical property tests and the possible degradation mechanism was also provided.…”

Section: Introductionmentioning

confidence: 99%

Structural Evolution of Polyglycolide and Poly(glycolide-co-lactide) Fibers during In Vitro Degradation with Different Heat-Setting Temperatures

et al. 2021

Self Cite

View full text Add to dashboard Cite

The structural evolution of polyglycolide (PGA) and poly(glycolide-co-lactide) (P(GA-co-LA)) with 8% LA content fibers with different heat-setting temperatures was investigated during in vitro degradation using WAXD, SAXS, and mechanical property tests. It was found that the PGA fiber was more susceptible to the degradation process than the P(GA-co-LA) fiber and a higher heat-setting temperature reduced the degradation rate of the two samples. The weight and mechanical properties of the samples showed a gradual decrease during degradation. We proposed that the degradation of PGA and P(GA-co-LA) fibers proceeded in four stages. A continuous increase in crystallinity during the early stage of degradation and a gradual decline during the later period indicated that preferential hydrolytic degradation occurred in the amorphous regions, followed by a further degradation in the crystalline regions. The cleavage-induced crystallization occurred during the later stage of degradation, contributing to an appreciable decrease in the long period and lamellar thickness of both PGA and P(GA-co-LA) samples. The introduction of LA units into the PGA skeleton reduced the difference in the degradation rate between the crystalline and amorphous regions, and they were simultaneously degraded in the early stage of degradation, leading to a degradation mechanism different from that of the PGA fiber.

show abstract

Structural Evolution of Polyglycolide and Poly(glycolide-co-lactide) Fibers during the Heat-Setting Process

Cited by 7 publications

References 47 publications

Degradation Behaviors of Polylactic Acid, Polyglycolic Acid, and Their Copolymer Films in Simulated Marine Environments

Degradation Behaviors of Polylactic Acid, Polyglycolic Acid, and Their Copolymer Films in Simulated Marine Environments

Structural responses of electrospun PVDF fibers induced by specific stretching and ensuing heating

Structural Evolution of Polyglycolide and Poly(glycolide-co-lactide) Fibers during In Vitro Degradation with Different Heat-Setting Temperatures

Contact Info

Product

Resources

About