Structural features and in vivo antitussive activity of the water extracted polymer from Glycyrrhiza glabra

Antitussive and immunomodulating activities of instant coffee arabinogalactan-protein

“…From the literature data it is evident that acidic polysaccharides mostly of rhamnogalacturonan types from medicinal plants Althaea officinalis L., Verbascum thapsiforme Schrad, Mahonia aquifolium (Pursh) Nutt, Salvia officinalis L., and Malva mauritiana L.were found to be the most active carbohydrates [24]. However, recently performed antitussive assays on arabinogalactan and rhamnogalacturonan rich water extracts of some Malian medicinal plants, Adhatoda vasica pectic arabinogalactan and highly branched arabinogalactan-protein from Glycyrrhiza glabra displayed as well promising antitussive activity [28][29][30]. In our immunobiological studies we have investigated also the possible immunomodulating activity of coffee AGP in term of TNF-␣, IFN-␥ and IL-2 cytokines production in the model systemsplenic cells.…”

Pharmacological Effects ofGlycyrrhizaspp. and Its Bioactive Constituents: Update and Review

“…suppressed coughing in a citric acid model in guinea pigs; application of this extract produced the strongest antitussive effect (81%) compared with other herbs (Nosalova et al, 2013). In another study (Saha et al, 2011), an aqueous extraction of polymeric fraction isolated from G. glabra (50 mg/kg, p.o.) showed similar effects and decreased the number of coughs produced by guinea pigs.…”

Antitussive and bronchodilatory effects of Lythrum salicaria polysaccharide-polyphenolic conjugate

“…Experimental studies on some above mentioned drugs revealed their antitussive effect and confirmed thus the positive curative influence of herbal plants used in traditional medicine. [27][28][29][30][31][32][33]. Similarly, the results of pharmacological tests pointed at the ability of L. salicaria polysaccharide-polyphenolic conjugate to suppress experimentally induced cough reflex in doses of 25 and 50 mg/kg bw, while higher dose (75 mg/kg bw), did not result in increased its antitussive activity.…”