Structural Features of Highly Stable Reproducible C₆₀Fullerene Aqueous Colloid Solution Probed by Various Techniques

Abstract

The m ethod of preparation of highly stable reproducible C60 fullerene aqueous colloid solution is described. The structural organization of C6o fullerenes in aqueous solution was studied and analyzed in detail using various techniques such as chemical analysis, U V /V IS spectroscopy, atomic force and scanning tunneling microscopy, dynamic light scattering, and zeta potential methods.

C60 fullerene affects elastic properties and osmoregulation reactions of human lymphocytes

“…The in-depth investigation of the structure and morphology of C 60 FAS was accomplished previously (Prylutskyy et al 2014b; Ritter et al 2015) and resulted in a view that the water solution of pristine fullerene molecules contains individual C 60 molecules and their bulk clusters with diameters dispersed in the range of 10−200 nm. Surface hydroxylation of C 60 molecules (exact number of attached hydroxyls is not yet known) is the most likely mechanism for pristine C 60 fullerenes/C 60 fullerene aggregates stabilization in water, being independent of the method of C 60 FAS preparation.…”

“…The structural organization of C 60 FAS was characterized earlier (Prylutskyy et al 2014b;Ritter et al 2015) by means of various physico-chemical methods.…”

Features of self-aggregation of C 60 molecules in toluene prepared by different methods

“…C 60 is soluble in many nonpolar organic solvents, such as toluene, benzene and xylene [2], is easily transferable into water [3]. The most probable mechanism of stability of C 60 fullerene aggregate/C 60 fullerene in water, regardless of the method of preparation of C 60 fullerene solution is the surface hydroxylation of C 60 molecules [4]. Fullerene C 60 has high lipophilicity [5], and is extremely valuable for innovative applications in medicine [6][7][8][9][10], chemical synthesis [11], catalysis [12], pharmacology [13], biomedical testing [14], electronics [15], solar energy [16] and optics [17][18][19].…”

Comparative Analysis of the Antineoplastic Activity of C60 Fullerene with 5-Fluorouracil and Pyrrole Derivative In Vivo

“…The nearly spherical C 60 molecule (diameter is 0.72 nm) can currently be routinely synthesized and is characterized by high chemical stability and biological activity in vitro and in vivo [1–4]. C 60 fullerenes are soluble in nonpolar organic solvents [5] and can be transferred into the water by means of special procedures [6–8]. These properties enable fullerene to utilize in biological objects due to their ability to easily penetrate the cell lipid membrane [9–12].…”