Abstract:SUMMARYThe earlier detection and investigation of babies with congenital structural heart disease has resulted in earlier treatment and better management of these patients. In
“…Since this time, an improvement in diagnostic, interventional and surgical techniques has produced an overall dramatic decrease in mortality and morbidity rates (British Cardiac Society 2002). Between 1965 and1975 in Canada, survival rates in the first month after surgery rose from 37% to 70% (Izukawa 1979). Between 1999 and 2006 in the US, overall mortality from congenital heart disease fell by 24.1% (Gilboa 2010).…”
“…Since this time, an improvement in diagnostic, interventional and surgical techniques has produced an overall dramatic decrease in mortality and morbidity rates (British Cardiac Society 2002). Between 1965 and1975 in Canada, survival rates in the first month after surgery rose from 37% to 70% (Izukawa 1979). Between 1999 and 2006 in the US, overall mortality from congenital heart disease fell by 24.1% (Gilboa 2010).…”
“…The hypoplastic left heart syndrome (HLHS) is itself a spectrum of congenital heart disorders characterized by marked underdevelopment of the structures of the left side of the heart (ascending aorta, aortic valve, ventricle, mitral valve and left atrium). It is relatively common and accounts for about 4% to 9% of congenital heart disease (Scott et al 1984, Fyler et al 1980, Izukawa et al 1979. Medical management has been generally unsuccessful and HLHS has been reported to cause 25% of cardiac deaths in the first week of life (Doty 1980).…”
We present the first case of Holt‐Oram syndrome associated with the lethal congenital heart defect of hypoplastic left heart syndrome. The possible pathophysiological link is explored and the need for careful genetic and cardiologic evaluation in these patients is reiterated.
“…Prospects for survival of such newborns have increased dramatically over the past 20 years, with palliation or correction now possible for many conditions [5,13,16,19]. However, there are data to suggest that the sickness-care system does not operate with an equal efficiency for all newborns who are at risk.…”
Section: Abstract: Heart Defects Congenital M Neonatology M Epidemimentioning
We collected data on 930 neonates with structural congenital heart disease seen during 1975-1977 at the existing pediatric cardiac referral and treatment centers in Ontario. Estimates were made of unmet need for pediatric cardiology services in Ontario. The data showed that a number of counties had significantly low referral rates and that at least 25% of the newborns with severe structural heart disease (that is, 75 newborns each year) were not seen by pediatric cardiologists, although the children would benefit from prompt assessment and rapid treatment under specialist supervision.
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