With the passage of time during pipeline operation, a substantial number of impurities accumulate and adhere to the inner wall of the pipeline. This deposition hinders the pipeline’s ability to function correctly, thereby posing significant hidden risks to people’s lives and the safety of their property. This article focuses on employing pipeline robots for internal cleaning. It examines the jet cleaning process of the spiral-driven pipeline inspection and cleaning robot, aiming to determine the optimal motion state and cleaning parameters for the device within the pipeline. The findings are verified and analyzed through experiments. It was observed that the cleaning effect is enhanced, with a target surface distance of approximately 12- to 13-times the diameter of the nozzle outlet (around 25 mm). In addition, an incident angle of 15° yields favorable cleaning results, with a maximum shear force exerted on the target surface of approximately 0.11 MPa. Ensuring that the pipelines operate reasonably and stably, thus guaranteeing their safe functioning and preventing significant economic and environmental damage, holds immense value.