1983
DOI: 10.1002/j.1460-2075.1983.tb01536.x
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Structural organization of the rat gene for the arginine vasopressin-neurophysin precursor

Abstract: The rat arginine vasopressin-neurophysin precursor gene has been isolated from a genomic library cloned in X phage Charon 4A. Restriction mapping and nucleotide sequence analysis demonstrated that the gene is 1.85 kilobase pairs long and contains two intervening sequences located in the protein coding region. Exon A encodes a putative signal peptide, the hormone arginine vasopressin and the variable N terminus of the carrier protein neurophysin, exon B encodes the highly conserved middle part of neurophysin an… Show more

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