Structural, Thermal and Optical Modifications of Chitosan due to UV-Ozone Irradiation

Abdel-Zaher, Nabawia A.; El‐Bassyouni, Gehan T.; Moselhey, Manal T. H.; Guirguis, Osiris W.

doi:10.21608/ejchem.2018.2904.1241

Cited by 5 publications

(5 citation statements)

References 27 publications

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“…Distinct ring patterns and the lattice points are visible in the SAED pattern shown in Figure F. The (110) and (020) lattice planes of chitosan are clearly seen in the SAED image, which is evidence of its crystallinity…”

Section: Resultsmentioning

confidence: 90%

“…The different layers of chitosan and gelatin formed by the twisting and rotation of polymeric chains are seen in Figure 9 E. As seen in the XRD pattern ( Figure 8 B), there is an increase in crystallinity of chitosan due to the encapsulation of dopamine. Distinct ring patterns and the lattice points are visible in the SAED pattern shown in Figure 9 F. The (110) and (020) lattice planes of chitosan are clearly seen in the SAED image, which is evidence of its crystallinity 48 …”

Section: Resultsmentioning

confidence: 91%

“…Distinct ring patterns and the lattice points are visible in the SAED pattern shown in Figure 9F. The (110) and (020) lattice planes of chitosan are clearly seen in the SAED image, which is evidence of its crystallinity 48 Drug Release Studies. The procedure followed to evaluate the drug release from the composite is described in Mathew et al 2020.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

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Crosslinked Chitosan–Gelatin Biocompatible Nanocomposite as a Neuro Drug Carrier

Mathew

2022

ACS Omega

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The polymers, chitosan, a polysaccharide, and gelatin, a protein, are crosslinked in different ratios without the aid of a crosslinking agent. Facile chemical reactions were followed to synthesize a chitosan/gelatin nanocomposite in three different ratios (1:1, 1:3, and 3:1). The solubility of chitosan and the stability of gelatin were improved due to the crosslinking. Both the polymers have excellent biodegradability, biocompatibility, adhesion, and absorption properties in a biological environment. The properties of the composite were favorable to be used in drug delivery applications, and the drug dopamine was encapsulated in the composite for all three ratios. The properties of the chitosan/gelatin nanocomposite and dopamine-loaded chitosan/gelatin nanocomposite were examined using XRD, FTIR, SEM, UV, TGA, TEM, and DLS techniques, and the crosslinking was confirmed. Higuchi kinetic release was seen with a cumulative release of 93% within 24 h for the 1:3 nanocomposite in a neutral medium. The peaks at 9 and 20° in the XRD spectrum confirmed the encapsulation of dopamine with the increase in the crystallinity of chitosan, which is also evident from the SAED image. The dopamine functional groups were confirmed from the IR peaks between 500 and 1500 cm –1 and the wide UV absorption maxima between 250 and 290 nm. The particle size of the drug-loaded composite in the ratios 1:1, 1:3, and 3:1 were calculated to be 275, 405, and 355 nm, respectively. The nanocomposite also showed favorable DPPH antioxidant and antibacterial activity against Staphylococcus aureus . Sustained release of dopamine in a neutral medium using crosslinked chitosan and gelatin without the presence of a crosslinker is the highlight of the work.

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Section: Resultsmentioning

confidence: 90%

Section: Resultsmentioning

confidence: 91%

Section: ■ Results and Discussionmentioning

confidence: 99%

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Crosslinked Chitosan–Gelatin Biocompatible Nanocomposite as a Neuro Drug Carrier

Mathew

2022

ACS Omega

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“…The XRD diffraction patterns of the chitosan and chitosan nanoparticles are shown in Fig. 2 Diffraction peaks at 2θ of 10.18°and 20.26°were observed in the chitosan powder, each of which is a reflection of the (020) hydrated crystalline structure and (110) crystalline structure of anhydrous αchitin [25]. The two diffraction peaks were also observed in the chitosan nanoparticles diffraction pattern.…”

Section: Resultsmentioning

confidence: 96%

Size-controlled chitosan nanoparticles prepared using ionotropic gelation

Budi¹,

Suliasih²,

Rahmawatia³

et al. 2020

ScienceAsia

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This work aimed at controlling the size of chitosan nanoparticles that were prepared by the ionotropic gelation method. Quantities of chitosan and sodium tripolyphosphate (STPP) were optimized to obtain a fine size and narrow size distribution of the nanoparticles. X-ray diffraction and selected area electron diffraction patterns indicated the existence of both crystalline and amorphous phases of chitosan. Particle size and size distribution were determined using transmission electron microscopy and dynamic laser scattering techniques. The size of the chitosan particles decreased with a reduction in STPP content due to a decrease in cross-link bonding and the formation of aggregate particles. Using this facile approach, the finest particles of chitosan were obtained in a range of 3-6 nm.

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“…One can obtain information regarding the structure of the sample including the crystalline symmetry, crystal defects, unit cell parameter, and texture of the sample. SAED has been used in the analysis of biopolymers to obtain information regarding their crystalline structure [184][185][186][187]. However, SAED is proven to be a more prominent technique in the analysis of the biopolymer-assisted synthesis of metallic nanoparticles [22,23,[188][189][190][191]; SAED analysis of biopolymer gum guar capped silver nanoparticles revealed information about the crystalline structure of the nanoparticles.…”

Section: Transmission Electron Microscopymentioning

confidence: 99%

Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives

et al. 2020

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Natural biopolymers, a class of materials extracted from renewable sources, is garnering interest due to growing concerns over environmental safety; biopolymers have the advantage of biocompatibility and biodegradability, an imperative requirement. The synthesis of nanoparticles and nanofibers from biopolymers provides a green platform relative to the conventional methods that use hazardous chemicals. However, it is challenging to characterize these nanoparticles and fibers due to the variation in size, shape, and morphology. In order to evaluate these properties, microscopic techniques such as optical microscopy, atomic force microscopy (AFM), and transmission electron microscopy (TEM) are essential. With the advent of new biopolymer systems, it is necessary to obtain insights into the fundamental structures of these systems to determine their structural, physical, and morphological properties, which play a vital role in defining their performance and applications. Microscopic techniques perform a decisive role in revealing intricate details, which assists in the appraisal of microstructure, surface morphology, chemical composition, and interfacial properties. This review highlights the significance of various microscopic techniques incorporating the literature details that help characterize biopolymers and their derivatives.

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Structural, Thermal and Optical Modifications of Chitosan due to UV-Ozone Irradiation

Cited by 5 publications

References 27 publications

Crosslinked Chitosan–Gelatin Biocompatible Nanocomposite as a Neuro Drug Carrier

Crosslinked Chitosan–Gelatin Biocompatible Nanocomposite as a Neuro Drug Carrier

Size-controlled chitosan nanoparticles prepared using ionotropic gelation

Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives

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