2023
DOI: 10.1021/acs.jnatprod.3c00498
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Structurally Diverse Cytotoxic Polyphenols from Garcinia gracilis

Yan-Song Ye,
Yao-Tao Duan,
Zhuo Zhou
et al.

Abstract: Thirty-five diverse polyphenols, belonging to seven structure classes, were isolated from Garcinia gracilis, a medicinal and edible plant sampled from Laos. The structures of nine new compounds, gargarcilones A−I (1−3, 5−7, 10, 12, and 17), were established using spectroscopic, X-ray diffraction, and experimental and calculated ECD methods. Additionally, we revised the stereochemical assignment of cochinchinoxanthone and cochinchinoxanthone C. The compounds were evaluated for antiproliferative activity against… Show more

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