2024
DOI: 10.1101/2024.07.03.601958
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Structure-based inference of eukaryotic complexity in Asgard archaea

Stephan Köstlbacher,
Jolien J. E. van Hooff,
Kassiani Panagiotou
et al.

Abstract: Asgard archaea played a key role in the origin of the eukaryotic cell. While previous studies found that Asgard genomes encode diverse eukaryotic signature proteins (ESPs), representing homologs of proteins that play important roles in the complex organization of eukaryotic cells, the cellular characteristics and complexity of the Asgard archaeal ancestor of eukaryotes remain unclear. Here, we usedde novoprotein structure modeling and sensitive sequence similarity detection algorithms within an expanded Asgard… Show more

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