Structure characterization and antitumor activity of an α β-glucan polysaccharide from Auricularia polytricha

Effect of γ -irradiation on antioxidant and antiproliferative properties of oat β -glucan

“…In vivo antitumor activity of α β-glucan extracted from Auricularia polytricha has also been reported and it was concluded that the degree of branching and the molecular weight may also influence the effectiveness of polysaccharides antitumor activity (Song and Du, 2012). The increased antiproliferative activity of oat β-glucan due to irradiation on human cancer cell lines might be due to the production of low molecular weight fragments by irradiation.…”

Structural identification and immunostimulating activity of a Laminaria japonica polysaccharide

“…Among these, macrophages have been shown to exert a variety of complex biological functions, such as phagocytosis, surveillance, chemotaxis and destruction of targeted organisms [12], suggesting the activation of macrophages might be a promising strategy to resist diseases. In recent years, polysaccharides extracted from different origins have attracted a great deal of attention in the biomedical area due to their broad spectrum of therapeutic properties and low toxicities [13][14][15]. Moreover, some natural polysaccharides have been reported to display a variety of beneficial pharmacological effects via modulating macrophage immune functions [16,17].…”

Physiological Active Substance Changes of Soybean Curd Residue Fermented by <i>Preussia aemulans</i> and its Bioactivity

“…Immunomodulation is the most notable biological function of natural polysaccharides, which is associated with their putative role as biological response modifiers (Moradali et al, 2007) and previous literature has been reported that the β-glycosidic linkage was the essential structural feature for immunostimulatory and antitumoral effects (Hung et al, 2008;Song et al, 2012). Therefore, the immunomodulatory activity of CPS fraction may be connected with the β-anomeric configuration.…”