Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies

Ganoderma lucidum Polysaccharides and Terpenoids: Profile and Health Benefits

“…A galactose rich extracellular polysaccharide composed of galactose, mannose, glucose, arabinose and rhamnose in different molar ratios and molecular weight was also isolated and identified in G. lucidum [30,31], and later Pan et al [32] isolated another neutral heteropolysaccharide containing galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22, respectively. Other polysaccharides containing xylose, fructose, glucose, sucrose and maltose in different molar ratios were also isolated and identified, and analysis has shown that maltose yielded more than 50% of the total saccharides [33].…”

Polysaccharide Production by Submerged Fermentation

“…Bioactive compounds from the different strains of G. lucidum can become very diverse depending on the geographic distribution of this fungus, growth conditions, and feedstocks (substrate). According to several reports (Pan et al 2012(Pan et al , 2013, the polysaccharidic extracts from G. lucidum present antioxidant activity and improve the immunity, so they have been suggested for the treatment of gastric cancer. The β-glucan from the macromycetes Grifola frondosa (known as Maitake beta-glucan or MBG) has been applied as coadjuvant for cancer treatment like chemotherapy (Lin et al 2010).…”

Isolation and identification of oxygenated lanostane-type triterpenoids from the fungus Ganoderma lucidum

“…Ganoderma lucidum (Polyporaceae) has been used in folk medicine throughout the world since ancient times, and it displays wide a potential medicinal value, especially for the treatment of neurasthenia, insomnia, anorexia, dizziness, chronic hepatitis, and other conditions (Cheng et al, 2012;Luo and Lin, 2002;Pan et al, 2012;Peng et al, 2013). On the basis of modern chromatographic and spectroscopic technologies, many chemical investigations on this fungus have been conducted to study its bioactive compounds.…”

“…To date, approximately 400 compounds have been obtained, including polysaccharides, triterpenoids, nucleotides, steroids, fatty acids, proteins, and peptides (Akihisa et al, 2005(Akihisa et al, , 2007Chien et al, 2004;Iwatsuki et al, 2003;Kawagishi et al, 1993;Luo and Lin, 2002;Luo et al, 2015;Wu et al, 2001). Among these, polysaccharides and triterpenoids were identified as the major bioactive substances in G. lucidum (Bao et al, 2002;Chien et al, 2004;Grienke et al, 2011;Kohda et al, 1985;Lee et al, 2010;Min et al, 2000;Sato et al, 2009;Pan et al, 2012). In particular, pharmacological effects of the triterpenoids from G. lucidum have increasingly been reported.…”