Structure of a novel α-glucan substitute with the rare 6-deoxy-d-altrose from Lactarius lividatus (mushroom)

Tako, Masakuni; Dobashi, Yahiko; Shimabukuro, Junpei; Yogi, Takuya; Uechi, Keiko; Tamaki, Yukihiro; Konishi, Teruko

doi:10.1016/j.carbpol.2012.11.010

Cited by 11 publications

(5 citation statements)

References 23 publications

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“…The 1 H and 13 C spectra of ALP-2 in D 2 O are presented in Figures d and c, which are similar to those of the reported α-glucan from Lactarius lividatus and Dictyophora echinovolvata . Combining all the assignments from the 2D COSY, HSQC, and HMBC spectrum, the proton chemical shifts (Table ) were completely assigned to 4-α-D-Glc p (A1), 4,6-α-D-Glc p (B1), and T-α-Glc p (C1), respectively.…”

Section: Resultssupporting

confidence: 74%

Glucans from Armillaria luteo-virens: Structural Characterization and In Vivo Immunomodulatory Investigation under Different Administration Routes

Liu,

Li,

Sun

et al. 2024

J. Agric. Food Chem.

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Polysaccharides fromArmillaria luteo-virens (ALP) were investigated for structural characterization and immunomodulatory activities. Three fractions (ALP-1, ALP-2, and ALP-3) were obtained with the yield of 2.4, 3.7, and 3.0 wt %, respectively. ALP-1 was proposed as a β-(1 → 3)(1 → 6)-glucan with a triple-helix conformation; ALP-2 and ALP-3 were both identified as α-(1 → 4)(1 → 6)-glucan differing in their M w and branching degree with a spherical conformation. The in vitro digestibility experiment and in vivo experiments using cyclophosphamide (CY)-treated mice demonstrated that intraperitoneal injection of α-glucan (1 mg•kg −1 •day −1 ) and intragastric gavage of β-glucan (10 mg•kg −1 •day −1 ) both effectively restored the decrease in body weight, immune organ indexes, immune cell activities, serum immune marker levels, colonic short-chain fatty acids (SCFA) levels, and Bacteroidetes/Firmicutes ratio in immunosuppression mice. This study provides novel insights into the immunomodulatory activity of αand β-glucans under different administration routes, thereby promoting their application in both food and pharmaceutical areas.

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Section: Resultssupporting

confidence: 74%

Glucans from Armillaria luteo-virens: Structural Characterization and In Vivo Immunomodulatory Investigation under Different Administration Routes

Liu,

Li,

Sun

et al. 2024

J. Agric. Food Chem.

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“…Recently, we discovered the novel deoxy-D-altrose [17] [18] and α-glucan [19] from the edible mushrooms. Especially, we isolated the novel acetylfucoidan from commercially cultured Cladosiphon okamuranus [5] and patented [20].…”

Section: Introductionmentioning

confidence: 99%

The Novel Pyruvated Glucogalactan Sulfate Isolated from the Red Seaweed, <i>Hypnea pannosa</i>

Tako¹,

Ohtoshi²,

Kinjyo³

et al. 2016

ABC

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“…An absorption at 3450 cm −1 was common to all the polysaccharides due to OH groups and an absorption at 2900 cm −1 was due to C-H stretching. Absorption common to galactomannan was observed in the range of 1245 -1000 cm −1 suggesting that the monosaccharide of the molecules consists of a pyranose ring [25] [31]. Absorption at 814 cm −1 was attributed to α-D-galactopyranose [25].…”

Section: Molecular Massmentioning

confidence: 93%

Discovery of Unusual Highly Branched Galactomannan from Seeds of <i>Desmanthus illinoensis</i>

Tako¹,

Tamaki²,

Teruya³

2018

JBNB

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A galactomannan was isolated from seeds of a leguminous plant, Desmanthus illinoensis, which is grown in Okinawa, Japan. D-Galactose (molar ratio, 1.0) and D-mannose (0.82) were identified via High-performance Anion Exchange Chromatography Coupled with a Pulse Amperometric Detector. The molecular mass and specific rotation were estimated to be 1000 kDa and +53.8˚, respectively. The infrared spectrum indicated that the galactomannan was involved in both α-and β-linkages, and two types of α-linkages were detected at 814 and 830 cm

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Structure of a novel α-glucan substitute with the rare 6-deoxy-d-altrose from Lactarius lividatus (mushroom)

Cited by 11 publications

References 23 publications

Glucans from Armillaria luteo-virens: Structural Characterization and In Vivo Immunomodulatory Investigation under Different Administration Routes

Glucans from Armillaria luteo-virens: Structural Characterization and In Vivo Immunomodulatory Investigation under Different Administration Routes

The Novel Pyruvated Glucogalactan Sulfate Isolated from the Red Seaweed, <i>Hypnea pannosa</i>

Discovery of Unusual Highly Branched Galactomannan from Seeds of <i>Desmanthus illinoensis</i>

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Structure of a novel α-glucan substitute with the rare 6-deoxy-d-altrose from Lactarius lividatus (mushroom)

Cited by 11 publications

References 23 publications

Glucans from Armillaria luteo-virens: Structural Characterization and In Vivo Immunomodulatory Investigation under Different Administration Routes

Glucans from Armillaria luteo-virens: Structural Characterization and In Vivo Immunomodulatory Investigation under Different Administration Routes

The Novel Pyruvated Glucogalactan Sulfate Isolated from the Red Seaweed, &lt;i&gt;Hypnea pannosa&lt;/i&gt;

Discovery of Unusual Highly Branched Galactomannan from Seeds of &lt;i&gt;Desmanthus illinoensis&lt;/i&gt;

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The Novel Pyruvated Glucogalactan Sulfate Isolated from the Red Seaweed, <i>Hypnea pannosa</i>

Discovery of Unusual Highly Branched Galactomannan from Seeds of <i>Desmanthus illinoensis</i>