In this paper, a control method of a novel tilt-rotor UAV with a blended wing body layout is studied. The novel UAV is capable of vertical take-off and landing and has strong stealth capabilities that can be applied to carrier-borne reconnaissance aircraft. However, the high aspect ratio of blended wing body UAVs leads to a wingtip or oar-tip touchdown problem when adopting the conventional position-attitude control (CPAC) scheme with a large crosswind disturbance. Moreover, when the UAV is subject to interference during reconnaissance, aerial photography, and landing missions, the conventional scheme cannot provide both attitude stability and track accuracy. First, a direct thrust vectoring control (DTVC) scheme is proposed. The control authority of the rotor tilt mechanism was added to enable the decoupling of the attitude and trajectory and to improve the response rate and response bandwidth of the flight trajectory. Second, considering the problems of strong couplings and parameter uncertainties and the nonlinear features and mismatched perturbations that are inevitable in the tilt-rotor, we designed a robust UAV controller based on the backstepping sliding mode control method and determined the stability of the control system through the Lyapunov function. Finally, in the case of crosswire interference during vertical takeoff and landing and the aerial photography missions of the UAV, the numerical simulation of the CPAC scheme and the DTVC scheme was carried out, respectively, and the Monte Carlo random test method was introduced to conduct the statistical test of the landing accuracy. The simulation results show that the DTVC scheme improves the landing accuracy and speed compared to the CAPC scheme and decouples the position control loop from the attitude control loop, finally enabling the UAV to complete the flight control in the VTOL phase.