Structures of Rare Earth Homodinuclear Macrocyclic Complexes with the Polyamine Polycarboxylic Ligand 1,4,7,10,14,17,20,23-Octaazacyclohexacosane-1,4,7,10,14,17,20,23-octaacetic Acid (H8OHEC) in the Crystal and in Solution

Schumann, Herbert; Böttger, U.; Weißhoff, Hardy; Ziemer, Burkhard; Zschunke, A.

doi:10.1002/(sici)1099-0682(199910)1999:10<1735::aid-ejic1735>3.0.co;2-3

Cited by 9 publications

(3 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hovland and coIn the last decades, nuclear magnetic resonance imaging has evolved as a powerful tool for research and practice in workers prepared a novel Gd(III)-87 complex, which showed high T 1 -relaxivity values in serum albumin solutions, blood and plasma [99]. membered ring formed from the eight amine and bridging ethylene or propylene groups, was synthesized and its properties as a chelator for lanthanides and small transition metals also was studied [100][101][102][103]. For increasing the rotational correlation time compared with conventional DOTA and DTPA and obtaining previously unknown binuclear contrast agents with two closely sited gadolinium ions, H 8 OHEC (1,4,7,10,14,17,20,23-octaazacyclohexacosane-1,4,7,10,14,17,20,23-octaacetic acid) (88), which is a macrocyclic polyaminocarboxylate with a 26-atom-…”

Section: Contrast Agents For Magnetic Resonance Imagingmentioning

confidence: 99%

Medical Applications of Macrocyclic Polyamines

Liang

Wan²,

Li³

et al. 2006

CMC

View full text Add to dashboard Cite

Macrocyclic polyamines comprise a special group of heterocycles that bind different guests. Over the past decade, medical interest has focused on macrocyclic polyamines owning to their chemical and biological properties. The discovery and development of the bicyclam AMD3100 highlighted the clinical potential of such compounds in AIDS, cancer and stem-cell mobilization. Many macrocyclic polyamines and their transition metal complexes had the cytotoxic activities to tumors through binding DNA, cleaving DNA, crosslinking DNA, or depleting the endogenous ATP levels of the tumor cells. Furthermore, macrocyclic polyamines also could be labeled with metal ionic radii and have applications in cancer radioimmunotherapy and in vivo magnetic resonance imaging (MRI). The current rational design, and medical applications of macrocyclic polyamines will be reviewed in this manuscript.

show abstract

Section: Contrast Agents For Magnetic Resonance Imagingmentioning

confidence: 99%

Medical Applications of Macrocyclic Polyamines

Liang

Wan²,

Li³

et al. 2006

CMC

View full text Add to dashboard Cite

show abstract

“…Eu III , Gd III and Tb III complexes of a branched hexaazacyclododecane ligand containing six 2,2 -bipyridine pendants units 9 or Y III , Gd III , Eu III and La III complexes of a polyamine polycarboxylic ligand. 10 With ligand L1 crystals suitable for X-ray diffraction could be obtained with europium and lanthanum by slow evaporation of the solvent. The dinuclear lanthanum complex is shown in Fig.…”

Section: Metal Complex Synthesismentioning

confidence: 99%

Synthesis of a novel dinucleating aminocarboxylate macrocycle and structures of its dinuclear complexes with di- and trivalent transition and lanthanide metal ions

2005

View full text Add to dashboard Cite

The synthesis of the new ligand L1(H4L1= 3,8,16,21-tetrakis(carboxylmethyl)-3,8,16,21,27,28-hexaazatricyclo[21.3.1.1(10,14)]octacosa-1(27),10,12,14(28),23,25-hexaen-5,18-diine) is reported. The solid-state structures of the four homodinuclear chelate complexes, [Zn2(L1)(H2O)2] x 6H2O, [Fe2(L1)(mu-O)] x 4H2O, [La2(L1)(NO3)2(H2O)2] x 6H2O and Na[Eu2(L1)(mu-AcO)3] x 3H2O, were determined by single-crystal X-ray structural analysis.

show abstract

“…The majority of structurally characterized complexes of REE with amino carboxylate ligands, however, have been produced at elevated pH (in the range 8.5–10), featuring chelation with involvement of amino groups into complexation 38 39 40 . It is thus surprising that very little has been studied so far about adsorption by nanomaterials under different pH conditions.…”

mentioning

confidence: 99%

Unusual seeding mechanism for enhanced performance in solid-phase magnetic extraction of Rare Earth Elements

Legaria

Rocha

Tai

et al. 2017

Sci Rep

View full text Add to dashboard Cite

Due to the increasing demand of Rare Earth Elements (REE or RE), new and more efficient techniques for their extraction are necessary, suitable for both mining and recycling processes. Current techniques such as solvent extraction or solid adsorbents entail drawbacks such as using big volumes of harmful solvents or limited capacity. Hybrid nanoadsorbents based on SiO2 and highly stable γ-Fe2O3-SiO2 nanoparticles, proved recently to be very attractive for adsorption of REE, yet not being the absolute key to solve the problem. In the present work, we introduce a highly appealing new approach in which the nanoparticles, rather than behaving as adsorbent materials, perform as inducers of crystallization for the REE in the form of hydroxides, allowing their facile and practically total removal from solution. This induced crystallization is achieved by tuning the pH, offering an uptake efficiency more than 20 times higher than previously reported (up to 900 mg RE3+/g vs. 40 mg RE3+/g). The obtained phases were characterized by SEM-EDS, TEM, STEM and EFTEM and 13C and 29Si solid state NMR. Magnetic studies showed that the materials possessed enough magnetic properties to be easily removed by a magnet, opening ways for an efficient and industrially applicable separation technique.

show abstract

Structures of Rare Earth Homodinuclear Macrocyclic Complexes with the Polyamine Polycarboxylic Ligand 1,4,7,10,14,17,20,23-Octaazacyclohexacosane-1,4,7,10,14,17,20,23-octaacetic Acid (H8OHEC) in the Crystal and in Solution

Cited by 9 publications

References 38 publications

Medical Applications of Macrocyclic Polyamines

Medical Applications of Macrocyclic Polyamines

Synthesis of a novel dinucleating aminocarboxylate macrocycle and structures of its dinuclear complexes with di- and trivalent transition and lanthanide metal ions

Unusual seeding mechanism for enhanced performance in solid-phase magnetic extraction of Rare Earth Elements

Contact Info

Product

Resources

About