Kawasaki disease (KD) is a common vasculitis syndrome that mainly affects children. Latent tuberculosis infection (LTBI) is a tuberculosis (TB) infection without signs or symptoms. Here, we report the case of a boy who traveled from abroad, was diagnosed with KD at our hospital, and underwent multidisciplinary treatment, including anti-TNFα therapy. Subsequently, the patient was found to have LTBI and was administered anti-TB treatment. To the best of our knowledge, this is the first reported case of LTBI in a KD patient receiving immunosuppressive therapy containing anti-TNFα.