Struma ovarii in a patient with a history of papillary thyroid carcinoma

Ng, Lydia; Brennan, Barbara A.

doi:10.1080/00313020600922405

Cited by 2 publications

(3 citation statements)

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“…While approximately 15% of all teratomas contain a small, nonsignificant focus of thyroid tissue, the definition of struma ovarii is an ovarian tumor with thyroid tissue occupying greater than 50% of the lesion ( 2 ). The gross appearance differs from a mature cystic teratoma, as it is often solid-cystic in architecture and may consist of a mixture of hemorrhagic, fibrotic, necrotic, and amber-colored thyroid tissues ( 1 , 3 ). The majority of these tumors are nonfunctional, and only 3% to 8% of patients present with hyperthyroidism.…”

Section: Introductionmentioning

confidence: 99%

“…Struma ovarii is most common in an older age group, with the majority of cases occurring between ages 40 and 60 years ( 4 ). Women with struma ovarii may present with pelvic pain and/or an asymptomatic pelvic mass ( 3 ). For the majority of patients, struma ovarii is benign and carries an excellent prognosis ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

“…Struma ovarii is very uncommon, accounting for less than 3% of all mature cystic ovarian teratomas ( 3 ). Pre-operative diagnosis is difficult, because this rare tumor has no differentiating signs or symptoms ( 6 , 7 ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incidental scintigraphic detection of struma ovarii following total thyroidectomy for papillary thyroid cancer

Wagner¹,

Hicks²,

Nakamura³

2011

Radiology Case Reports

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A postmenopausal female presented with an enlarging multinodular goiter. Microcalcifications within the largest thyroid nodule found by ultrasound prompted her to elect a total thyroidectomy. Histopathologic evaluation led to the diagnosis of confined papillary thyroid carcinoma (follicular variant). Elevated serum thyroglobulin levels were noted on postoperative laboratory workup, with the differential diagnosis of residual thyroid tissue, substernal extension of an adenomatoid multinodular goiter, and/or metastatic thyroid cancer. The patient then underwent thyrogen-stimulated I-131 ablation therapy, with postablation scans detecting a solitary focus of intensely increased radiotracer accumulation in the midline pelvis. Ultrasound of the pelvis revealed a corresponding right ovarian mass with mixed solid and cystic components. These combined findings were highly suggestive of struma ovarii. An exploratory laparotomy/bilateral salpingo-oophorectomy was performed, and pathologic examination confirmed a mature teratoma with predominant benign thyroid component consistent with struma ovarii.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%