Key Points
The overall incidence of rescue THV‐in‐THV is low (1%). It is diminishing over time, and occurs to a lesser extent with the newer generation TAVR platforms.
Rescue THV‐in‐THV is usually performed for valve mal‐positioning with or without significant aortic regurgitation.
A rescue THV‐in‐THV procedure is associated with higher in‐hospital mortality and complications, but acceptable intermediate‐term outcomes among hospital survivors.