Studi Literatur: Tinjauan Pemeriksaan  Laboratorium pada Pasien COVID-19

Mus, Rosdiana; Thaslifa, Thaslifa; Abbas, Mutmainnah; Sunaidi, Yanti

doi:10.22146/jkesvo.58741

Cited by 11 publications

(10 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…24 An elevated neutrophil lymphocyte ratio will be the outcome of elevated neutrophils and decreased lymphocytes. 11 It is known that when SARS-CoV-2 enters the respiratory tract, it will go to the alveolar epithelial cells and attach to its specific receptor, namely Angiotensin Converting Enzyme 2 (ACE-2). Furthermore, the virus will undergo several processes that release new viruses from replication into the body's cells.…”

Section: Resultsmentioning

confidence: 99%

“…This can cause an imbalance in body's immune response, where the number of neutrophils increases as an inflammatory response infection and a decrease in lymphocytes indicates an inflammatory process. [11][12][13] The NLR examination can be assessed when the patient is admitted to the hospital for screening, classifying and evaluating the patient's prognosis to determine the initial phase of the COVID-19 disease course. This is done to help medical personnel make early detection and earlier management of patients to achieve better outcomes.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Relationship Between Neutrophil Lymphocyte Ratio and Clinical Spectrum of Covid-19 Patients at Rsud Tugurejo Semarang

Amirah

2023

dmj

View full text Add to dashboard Cite

Background: Coronavirus Disease 2019 (COVID-19) is an infectious respiratory disease caused by infection novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 patients has different clinical spectrum, it depends on individual susceptibility and virus ability to infect. Supporting examination that can be used to screening, monitoring and evaluating COVID-19 patient is Neutrophil to Lymphocyte Ratio. Elevated NLR result indicates an imbalance immune response because neutrophilia and lymphopenia occurs.Objective: This study to determine whether there is a relationship between neutrophil lymphocyte ratios with clinical spectrum of COVID-19 patients at Tugurejo Hospital, Semarang.Methods: The research conducted at Tugurejo Hospital Semarang in November 2022. This study was an analytical observasional study with cross sectional design and used consequtive sampling. Total samples are 99 fit into the inclusion criteria carried out by data from medical records. Data analysis used Chi Square Test to assess whether there is a relationship between both variable. Results: The age of COVID-19 patients who hospitalized was 19 – 91 years old. Most of the clinical spectrum patients was moderate (49.5%) and neutrophil lymphocyte ratio result was ≥3.13 (high risk). On Chi Square test found the result of p-value is 0.045 (<0.05) between neutrophil lymphocyte ratio with the clinical spectrum of COVID-19 patients. Which meant that there was significant relationship between both variables.Conclusion: There is significant relationship between neutrophil lymphocyte ratio with clinical spectrum of COVID-19 patients at Tugurejo Hopsital Semarang.

show abstract

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Relationship Between Neutrophil Lymphocyte Ratio and Clinical Spectrum of Covid-19 Patients at Rsud Tugurejo Semarang

Amirah

2023

dmj

View full text Add to dashboard Cite

show abstract

“…Limfosit menurun bisa disebabkan oleh ditemukannya infeksi virus yang terjadi dalam tubuh yang disebabkan oleh sistem kekebalan tubuh yang rendah sehingga tubuh rentan terserang penyakit. Pada penelitia yang dilakukan oleh Mus et al, menyatakan penurunan jumlah limfosit ditemukan juga dalam penelitiannya yang menunjukkan bahwa virus (COVID-19) dapat menghambat sistem imun karena penurunan jumlah limfosit dapat menunjukkan kerusakan dalam sistem kekebalan tubuh (Mus et al, 2021).…”

Section: Gambaranunclassified

Gambaran Karakteristik Pasien Covid-19 di Rumah Sakit Mekar Sari Bekasi Tahun 2020-2021

et al. 2022

View full text Add to dashboard Cite

Pada tanggal 7 Januari 2020, China mengidentifikasi kasus pneumonia yang tidak diketahui etiologinya sebagai jenis baru coronavirus atau biasa disebut COVID-19 Penelitian ini merupakan penelitian deskriptif kuantitatif dengan desain crosssectional. Penelitian dilakukan di Rumah Sakit Mekar Sari Bekasi dengan sampel 220 pasien COVID-19. Hasil penelitian menunjukan SPO tatalaksana pasien COVID-19 di Rumah Sakit Mekar Sari Bekasi menggunakan Pedoman Pencegahan dan Pengendalian COVID-19 oleh Kemenkes. Untuk karakteristik pasien pasien berjenis kelamin perempuan (50,9%). Kategori usia paling banyak adalah 46-59 Tahun (37,3%). Pekerjaan paling banyak non-medis (85,5%). Berdomisili di Kota Bekasi (69,1%). Gejala yang paling banyak dirasakan adalah batuk (84,1%). Tidak memiliki kondisi penyerta (59,5% ) tetapi kondisi penyerta paling banyak Hipertensi (22,3%). Hasil swab antigen positif (100%). Hasil PCR Positif (69,5%). Limfosit menurun (55,9%). Hasil X-Ray tidak normal (75,5%). Tidak memiliki riwayat kontak dan paparan virus (66,4%). Memiliki riwayat kontak dengan pasien COVID-19 (15,9%). Kriteria pasien terkonfirmasi COVID-19 (72,3%). Saat pulang pasien masih harus melakukan Isolasi Mandiri (39,5%). Kodefikasi kasus dengan ICD-10. Masyarakat harus mematuhi protokol kesehatan untuk pencegahan dan pengendalian kasus COVID-19 di Indonesia.

show abstract

“…Pemantauan kadar D-dimer pada pasien COVID-19 merupakan metode yang sederhana dan cepat untuk memprediksi prognosis penyakit. (Mus, Thaslifa, Abbas, & Sunaidi, 2021) Saturasi oksigen merupakan nilai yang menunjukkan kadar oksigen dalam darah dan juga dapat digunakan sebagai parameter distress napas pada pasien COVID-19. Sirkulasi oksigen pada pasien COVID-19 cenderung terhambat karena adanya penumpukan cairan pada parenkim paru akibat adanya infeksi virus (Shenoy et al, 2020).…”

Section: Pendahuluanunclassified

Analysis of the Relationship between Laboratory Biomarkers and the Severity of COVID-19 at Kaliwates General Hospital Jember

Akbar¹,

Rahardjo

Parti

et al. 2022

AMS

View full text Add to dashboard Cite

Coronavirus Disease 2019 (COVID-19) has become a global health problem since the WHO declared the disease a pandemic. In July 2021, Indonesia experienced a very sharp spike in cases and an increase in mortality due to COVID-19, including at the Kaliwates General Hospital in Jember. Laboratory biomarkers in the form of Neutrophile Lymphpocyte Ratio (NLR), D-dimer, and SpO2 can be a clue to assess the severity of COVID-19 patients. This research is an observational analytical study using a Cross Sectional Study with the aim of knowing the relationship between laboratory biomarkers and the severity of COVID 19 at RSU Kaliwates Jember. This study uses secondary data in the form of medical records of COVID-19 patients during July 2021 with a total of 50 samples. The results of this study were carried out by the Spearman correlation test and it was found that there was a correlation between NLR values and oxygen saturation with the severity of COVID-19, but there was no relationship between D-dimer levels and the severity of COVID-19. The conclusion of this study is that NLR biomarkers and oxygen saturation can be used as predictors of the severity of COVID-19.

show abstract

Studi Literatur: Tinjauan Pemeriksaan Laboratorium pada Pasien COVID-19

Cited by 11 publications

References 9 publications

Relationship Between Neutrophil Lymphocyte Ratio and Clinical Spectrum of Covid-19 Patients at Rsud Tugurejo Semarang

Relationship Between Neutrophil Lymphocyte Ratio and Clinical Spectrum of Covid-19 Patients at Rsud Tugurejo Semarang

Gambaran Karakteristik Pasien Covid-19 di Rumah Sakit Mekar Sari Bekasi Tahun 2020-2021

Analysis of the Relationship between Laboratory Biomarkers and the Severity of COVID-19 at Kaliwates General Hospital Jember

Contact Info

Product

Resources

About