Studies Concerning DDW Use for Deuterium Depletion in the Organism of Laboratory Animals

Abstract

Administration of DDW (deuterium depleted water) represents a proper method to reduce deuterium in biological systems. In present study experiments were performed in order to observe the deuterium's concentration decrease in laboratory animals' bodies using DDW as depleting agent, the main ingredient for the commercial product QLARIVIA™ 2. Deuterium depletion studies were elaborated on laboratory animals, nourished with standard food and drinking water, respectively DDW. Biological samples were analyzed through mass-spectrometry. The results showed that in natural conditions, the mammals' organisms have the tendency to accumulate deuterium through bioaccumulation process. As a conclusion it can be noticed that the grade of deuterium depletion from mammals' bodies seems to be especially under the influence of DDW's concentration and of administration's period of time.

Possible Mechanisms of Biological Effects Observed in Living Systems during 2H/1H Isotope Fractionation and Deuterium Interactions with Other Biogenic Isotopes

“…For a more complete understanding of the effects observed when individual fractions of heavy or light isotopes accumulate, the key mechanisms for the realization of their bioeffects should be considered. This approach requires detailed analysis, as it has been shown by different scientific groups that metabolic processes in the body can be influenced (stimulated or inhibited) by both decreases and increases within the same range in the amount of heavy isotopes in comparison with their natural levels in the environment [34,35,36,37,38].…”