“…The research presented in this thesis is motivated by the significant changes that the digital transformation and ever-increasing use of automation solutions and other advanced technologies may cause in the design and operation of safetycritical systems. For example, conventional hardwired analog interface technology based NPP control rooms undergo extensive modifications when the automation systems are modernized (Nystad et al, 2011). The work of surgeons will also change when advanced robot surgery solutions are deployed in operating theaters (Aaltonen & Wahlström, 2018).…”