Studies in avian adrenal steroid function

Pekin ducks (Anas platyrhynchos) were bilaterally adrenalectomized (ADX) using a two-stage procedure and given daily i.m. injections of 1 mg kg bw(-1) of dexamethasone (DEXA), a steroid lacking mineralocorticoid activity, and 0.9% saline drinking water ad libitum to counterbalance renal losses of salt and water. Mean arterial blood pressure (mmHg) fell from 161+/- 3.7 (intact controls) to 116 +/- 6.9 (bilateral ADX+DEXA), a decrease of 27%, but heart rates (HR) were unchanged. The nasal salt glands were fully active after ADX + DEXA. Rates of fluid secretion and electrolyte and osmolal concentrations were unchanged. Secretion stopped, then rebounded several minutes later if ADX + DEXA ducks were injected i.v. with 1 microg of [Asn(1),Val(5)]-angiotensin II (ANG II) kg bw(-1) which showed that attenuation was not adrenal catecholamine-dependent.

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Studies in avian adrenal steroid function

Thomas

Phillips

1975

General and Comparative Endocrinology

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Studies in avian adrenal steroid function

Cited by 18 publications

References 99 publications

Effect of saline acclimation on body water and sodium compartmentalization in Pekin ducks (Anas platyrhynchos)

Effect of saline acclimation on body water and sodium compartmentalization in Pekin ducks (Anas platyrhynchos)

ANG II-induced attenuation of duck salt gland secretion does not depend upon the release of adrenal catecholamines

Studies in avian adrenal steroid function

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