Studies in Humans

Hayes, Wayland J.; Bruckner, James V.; Doull, John

doi:10.1016/b978-0-12-374367-1.00059-8

Cited by 3 publications

(1 citation statement)

References 396 publications

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“…But the KDT50 of deltamethrin 0.05%, lambda-cyhalothrin (0.05%), pirimiphos methyl (0.25%) and fenitrothion (1.0%) ranged from more than 60 minutes against An.funstus. This may be due to the slowing of vector uptake and behavioral adaptation and subsequent inhibition of vector cholinesterase (96,97). In contrast, the 90% KDT time of these insecticides were wider for both An.…”

Section: Discussionmentioning

confidence: 91%

Susceptibility Status of Principal Malaria Vectors to Insecticides Commonly Used for Malaria Control in Africa: Meta-analysis and Systemic review

Minwuyelet

Yewhalaw

Sciarretta

et al. 2023

Preprint

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Background: Malaria is a major public health problem in the African region. Nearly the last one century, various types of insecticides have been used to reduce malaria transmission and vector control. However, the effectiveness of insecticides decreases periodically. This study aimed to assess the susceptibility status of major malaria vectors to insecticides commonly used to control malaria in Africa. Methods: We used the public database: PubMed, Google Scholar, Scopus, and Pro-Quest to access relevant articles published between 2002 and 2021. Primary articles were searched using keywords such as "Susceptibility status", "insecticide resistance", "malaria vector", "Africa", and "Anopheles". The search was conducted from September 25th to October 15th, 2022. The review included primary articles published in English from 2002 to 2021 and articles with all the required information. Data were extracted from the included article texts, tables, figures, and supplementary files. The validity of all included articles was checked prior to inclusion by critical evaluation using standardized means. Finally, the results of the original article were presented in tables, graphs, and maps. Results: Fifty related articles were retrieved and extracted from the 1742 accessed articles. Of these, most articles showed resistance of Anopheles gambiae sensu lato(sl) and An.funestus to organochlorines: DDT (4%), cyclodins: dieldrin (4%), pyrethroids:lambda-cyhalothrin (0.05%), cyfluthrin (0.15%), permethrin (0.75%), carbamate: deltamethrin (0.05%) and propoxur (0.1%), across Africa. These insecticides also showed knockdown resistance to malaria vectors prevalent in Africa. However, the resistance of these malaria vectors varied in different parts of the continent and in different countries. Between 2010 and 2015, Africa recorded the highest resistance to insecticides. In recent years, organophosphates have received considerable attention as candidate chemicals for residual spray in malaria control programs. Conclusions: An. gambiae s.l. and An. funestus has been developed resistant to three classes of pesticides (pyrethroids, carbamates, and organochlorines). To prevent and manage malaria vectors in Africa, only organophosphate groups, particularly pirimiphos methyl 0.25% and a neonicotinoid like clothianidin, are advised. In addition, it is urgently necessary to scale up insecticide use, introduce new insecticides, and use additional biological control strategies.

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Section: Discussionmentioning

confidence: 91%