Studies in hypersensitiveness in certain dermatoses

Sulzberger, Marion B.; Spain, W.C.; Sammis, Florence E.; Shahon, H.I.

doi:10.1016/s0021-8707(32)90177-4

Cited by 40 publications

(4 citation statements)

References 9 publications

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“…Dysplasia is as enigmatic and imprecise a term in general pathology as eczema is in clinical dermatology (Sulzberger 1932, Ackerman & Ragaz 1982. No two pathologists or dermatologists seem able to define these words in the same way, a phenomenon I refer to as 'pathobabel' and 'dermatobabel' in reference to the biblical tower where a confusion of tongues impeded communication (Ackerman 1980a).…”

Section: Confusion About Dysplasiamentioning

confidence: 99%

What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer

Ab¹

1988

Histopathology

121

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This assay examines critically the concept of 'dysplasia' as it applies to melanocytic neoplasia and concludes that the concept is flawed. Doubt is cast also upon the validity of the concepts of a dysplastic naevus and a dysplastic naevus syndrome. The author is of the view that most malignant melanomas arise de novo and not in pre-existing dysplastic naevi. Because so-called dysplastic naevi are considered by the author to be the commonest melanocytic naevi in man and devoid of nuclear atypia, he proposes that they be re-named 'common naevi' in the interest of simplicity, accuracy, and care of patients. Lastly, it is suggested that resolution of problems in the sphere of melanocytic neoplasia might be accomplished more readily were terms like dysplasia, dysplastic cells, dysplastic naevi, and the dysplastic naevus syndrome eschewed.

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Section: Confusion About Dysplasiamentioning

confidence: 99%

What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer

Ab¹

1988

Histopathology

121

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“…In 1923, Coca and Cooke [ 9 ] first reported that asthma and hay fever are specifically compartmentalized in individuals or family members who were hypersensitive to various external antigens, and they proposed the use of the term "atopy" for these mysterious phenomena. Meanwhile, the close association of certain types of itchy eczema with asthma and hay fever again drew special attention by Low as an eczema-asthma-prurigo complex or by Drake as an asthma-eczema-prurigo complex in 1928 [ 8 , 10 ], leading to the proposal of "atopic dermatitis/eczema" [ 5 , 11 , 12 ]. Even in the early 1930s, basic concepts for AD had been postulated: 1) family history of atopy; 2) antecedent infantile eczema; 3) preponderance on antecubital and popliteal fossae, anterior neck, chest, face and eyelids; 4) skin hyperpigmentation; 5) no appreciable vesicle formation as is usually clinically and histologically found in contact dermatitis; 6) unstable or hypersensitive vasomotor neuron reaction; 7) negative patch test reaction to most contact allergens; 8) positive skin test reaction to various environmental and food allergens; and 9) positive serum reaginic activity (=IgE) as detected by Prausnitz-Küstner reaction [ 11 - 13 ].…”

Section: Introductionmentioning

confidence: 99%

Current status of atopic dermatitis in Japan

Furue

Chiba

Takeuchi

2011

Asia Pacific Allergy

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Atopic dermatitis (AD) is a common, chronic or chronically relapsing, severely pruritic, eczematous skin disease. AD is the second most frequently observed skin disease in dermatology clinics in Japan. Prevalence of childhood AD is 12-13% in mainland Japan; however, it is only half that (about 6%) in children from Ishigaki Island, Okinawa. Topical steroids and tacrolimus are the mainstay of treatment. However, the adverse effects and emotional fear of long-term use of topical steroids have induced a "topical steroid phobia" in patients throughout the world. Undertreatment can exacerbate facial/periocular lesions and lead to the development of atopic cataract and retinal detachment due to repeated scratching/rubbing/patting. Overcoming topical steroid phobia is a key issue for the successful treatment of AD through education, understanding and cooperation of patients and their guardians.

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“…The recording of a ballistocardiogram would require more extensive modification of the apparatus than when a phonocardiogram is used but would appear feasible and might give valuable information on the nature of some components of the ballistocardiogram that are not completely understood. 9 The apparatus could also be modified to record simultaneously a phonocardio¬ gram and an electrocardiogram.…”

Section: Methodsmentioning

confidence: 99%

High-Speed Cineradiography and Electrocardiography

Prinzmetal¹

1956

JAMA

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Studies in hypersensitiveness in certain dermatoses

Cited by 40 publications

References 9 publications

What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer

What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer

Current status of atopic dermatitis in Japan

High-Speed Cineradiography and Electrocardiography

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