Studies of cancer in migrants: Rationale and methodology

Parkin, Donald Maxwell; Khlat, Myriam

doi:10.1016/0959-8049(96)00062-7

Cited by 148 publications

(129 citation statements)

References 30 publications

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“…North American and East European countries harbor multiethnic and multicultural societies and as immigrants are self-selected groups, therefore samples from such countries might not represent the population of country of origin. 36 However, the observed risk of endometrial cancer among other first-generation immigrants in our study is in agreement with the report of CI5. 1 It has been observed that the age at immigration was almost three decades earlier than the age at diagnosis of endometrial cancer.…”

Section: Discussionsupporting

confidence: 92%

Morbidity and mortality in gynecological cancers among first‐ and second‐generation immigrants in Sweden

Mousavi

Sundquist

Hemminki

2011

Intl Journal of Cancer

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We studied the effect of new environment on the risk in and mortality of gynecological cancers in first-and second-generation immigrants in Sweden. We used the nationwide Swedish Family-Cancer Database to calculate standardized incidence/mortality ratios (SIRs/SMRs) of cervical, endometrial and ovarian cancers among immigrants in comparison to the native Swedes. Risk of cervical cancer increased among first-generation immigrants with Danish (SIR 5 1.64), Norwegian (1.33), former Yugoslavian (1.21) and East European (1.35) origins, whereas this risk decreased among Finns (0.88) and Asians (SIRs varies from 0.11 in Iranians to 0.54 in East Asians). Risk of endometrial (SIRs varies from 0.28 in Africans to 0.86 in Finns) and ovarian (SIRs varies from 0.23 in Chileans to 0.82 in Finns) cancers decreased in first-generation immigrants. The overall gynecological cancer risk for the second-generation immigrants, independent of the birth region, was almost similar to that obtained for the first generations. The birth region-specific SMRs of gynecological cancers in first-and second-generation immigrants co-varied with the SIRs. Risk of gynecological cancers among the first-generation immigrants is similar to that in their original countries, except for cervical cancer among Africans and endometrial cancer among North Americans and East Europeans. Our findings show that risk and mortality of gynecological cancers observed in the first-generation immigrants remain in the second generation. We conclude that the risk and protective factors of gynecological cancers are preserved upon immigration and through generations, suggesting a role for behavioral factors or familial aggregation in the etiology of these diseases.

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Section: Discussionsupporting

confidence: 92%

Morbidity and mortality in gynecological cancers among first‐ and second‐generation immigrants in Sweden

Mousavi

Sundquist

Hemminki

2011

Intl Journal of Cancer

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“…The increasing trend in relative risk of death among Asian migrants from cancers of the colon/rectum, breast and prostate with time since migration to a westernized country were in accord with what would be expected (Parkin and Khlat, 1996;. Armstrong et al (1983) showed a similar pattern for migrants from Italy and Greece to Australia but did not report on trends in Asian migrants.…”

Section: Discussionsupporting

confidence: 66%

Cancer mortality in East and Southeast Asian migrants to New South Wales, Australia, 1975–1995

1999

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Routinely collected data for New South Wales were used to analyse cancer mortality in migrants born in East or Southeast Asia according to duration of residence in Australia. A case-control approach compared deaths from cancer at particular sites with deaths from all other cancers, adjusting for age, sex and calendar period. Compared with the Australian-born, these Asian migrants had a 30-fold higher risk of dying from nasopharyngeal cancer in the first 2 decades of residence, falling to ninefold after 30 years, and for deaths from liver cancer, a 12-fold risk in the first 2 decades, falling to threefold after 30 years. The initial lower risk from colorectal, breast or prostate cancers later converged towards the Australian-born level, the change being apparent in the third decade after migration. The relative risk of dying from lung cancer among these Asian migrants was above unity for each category of duration of stay for women, but at or below unity for men, with no trend in risk over time. An environmental or lifestyle influence for nasopharyngeal and liver cancers is suggested as well as for cancers of colon/rectum, breast and prostate. © 1999 Cancer Research Campaign

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“…Migrant studies have shown that after successive generations, breast cancer incidence in Asian women becomes similar to that of Western countries (Trichopoulos et al, 1984;Ziegler et al, 1984;Stanford et al, 1995;Kaur, 2000). Furthermore, an increasing incidence of breast cancer among Chinese women parallels the Westernization of the Chinese diet, which suggesting that the difference in breast cancer incidence rates between Western and Eastern women are mainly influenced by the lifestyle and diet habits rather than genetics (Parkin et al, 1996).…”

Section: Introductionmentioning

confidence: 99%

Study on Soy Isoflavone Consumption and Risk of Breast Cancer and Survival

Hj¹,

Zhang²,

Yang³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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Asian Pacific J Cancer Prev, 13, 995-998 IntroductionBreast cancer is by far the most frequent cancer among women with an estimated 1.38 million new cancer cases diagnosed in 2008 (23% of all cancers), and ranks second overall (10.9% of all cancers). It is now the most common cancer both in developed and developing regions with around 690,000 new cases estimated in each region (population ratio 1:4). Incidence rates vary from 19.3 per 100,000 women in Eastern Africa to 89.7 per 100,000 women in Western Europe, and are high (greater than 80 per 100,000) in developed regions of the world (except Japan) and low (less than 40 per 100,000) in most of the developing regions. The high incidence of the cancer in certain geographic regions suggests the role of environmental risk factors in pathogenesis of breast cancer (IARC, 2008).As we known, isoflavones in soy foods are part of a larger class of flayonoid compounds that have have been demonstrated to be potent dietary anti-cancer agents (Reinli and Block, 1996). The primary isoflavones daidzein, genistein, and glycetin comprise 40, 50, and 10% of the soybean isoflavones, respectively (Murphy et al., 1999). Soy intake is high in many Asian countries where breast cancer incidence is lower compared to Western countries (Rose et al., 1986;Parkin, 1989;

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Studies of cancer in migrants: Rationale and methodology

Cited by 148 publications

References 30 publications

Morbidity and mortality in gynecological cancers among first‐ and second‐generation immigrants in Sweden

Morbidity and mortality in gynecological cancers among first‐ and second‐generation immigrants in Sweden

Cancer mortality in East and Southeast Asian migrants to New South Wales, Australia, 1975–1995

Study on Soy Isoflavone Consumption and Risk of Breast Cancer and Survival

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