Models available in literature for predicting drag reduction scale-up are inadequate as they have been successful only over a narrow range of diameters. A new scale-up model is presented which equates dampening of turbulent velocity fluctuations by drag reducing additives to a reduction in the Prandtl mixing length. Flow and pressure drop data from a laboratory scale pipe along with shear viscosity measurements are sufficient to predict drag reduction scale-up in bigger diameter pipes. Using this approach, scale-up was successfully predicted over a diameter range of 7 to 154 mm for a surfactant-water system and 26.6 to 1194 mm for a polymer-oil system. Les modeles presentes dans la litterature scientifique pour la prediction de la mise a I'echelle de la reduction de trainee sont inadequats, ceux-ci ne fonctionnant que dans une gamme etroite de he reduction in friction loss for turbulent flow through T circular pipes by addition of small amounts (measured in parts per million) of high molecular weight polymeric additives to a liquid, has been well documented over the last few decades. In recent times, the focus has shifted to surfactant solutions, forming rod like micelles, which at relatively higher concentrations produce reduction in drag by the same mechanism.Though polymeric additives were used by ARC0 Oil company in the Trans Alaska Pipeline for transporting crude oil (Burger et al., 1982) in the early 1980s, wide ranging commercial use of these additives was hampered by their susceptibility to mechanical degradation. Surfactant additives are highly resistant to mechanical degradation and are currently being used extensively in several European countries in district heating and cooling systems (Steiff et al., 1989) and in a library cooling system at Halifax, Canada (Young, 1996).Despite the general agreement that turbulent drag reduction is a consequence of the interaction of the viscoelastic additive molecules with the turbulent boundary layer (Virk, 1975) direct experimental verification of these properties is very difficult because of the low concentrations of these solutions. Though a large volume of work has been done on this subject, a theoretical expression or correlation which accurately predicts the turbulent friction loss characteristics of these solutions has not yet been obtained.The flow of Newtonian fluids in circular pipes can be adequately correlated by the well known universal laws: *Author to whom correspondence should be addressed. E-mail address: rhodes@tuns.ca Unlike Newtonian fluids, there is a rather strong influence of the pipe diameter on the friction law for drag reducing fluids. These solutions cannot be characterized by the Reynolds number of the flow. In other words, maintaining the same Reynolds number in different diameter pipes would not yield the same friction factor due to the so called 'Diameter Effect'. Tackling the problem of the diameter effect assumes considerable importance and interest, knowing that a complete and detailed description of the interaction of additive ...