Studies of Infective Endocarditis in Cardiomyoblasts H9c2 Cell Line

Abstract

Infective endocarditis (IE) is a condition that could possibly be induced by poor oral hygiene. Peptidoglycan (PGN) and lipoteichoic acid (LTA) promote cytokine expression and nitric oxide (NO) production by binding toll-like receptor (TLR)-2, considered the innate immune response initiator. Some studies have indicated that flavonoids possess antioxidant and anti-inflammatory properties. The aim of this review consisted in describe in vitro studies related to PGN and LTA in IE in H9c2 cell line.