Studies of physicochemical and chromatographic properties of mixed amino-alkylamide bonded phases

Buszewski, Bogusław; Jaroniec, Mietek; Gilpin, R. K.

doi:10.1016/0021-9673(94)87052-7

Cited by 56 publications

(22 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anilines have been separated in 100% aqueous mobile phases on alkylamide stationary phases (Buszewski et al 1994a). Buszewski has produced a series of papers studying the chromatographic properties of alkyl amide stationary phases, demonstrating that alkyl 3-amido propyl silicas possess enhanced peak symmetry (Buszewski et al 1994b) while chain length correlated with methylene selectivity (Buszewski et al 1994a). Czajkowska and Jaroniec reported that alkylamide bonded phases demonstrated superior selectivity in the separation of carboxylic acids (Czajkowska and Jaroniec 1997).…”

Section: Alkyl Amide Polar-embedded Stationary Phasesmentioning

confidence: 98%

Polar-Embedded and Polar-Endcapped Stationary Phases for LC

2010

View full text Add to dashboard Cite

Polar-embedded and polar-endcapped phases have become widespread over the past decade. When compared to classical alkylsilicas, they offer an alternative selectivity profile, increased stability in highly aqueous mobile phases, and improved peak shape for basic analytes. This mini-review summarizes current knowledge and applications of these phases, including the recent development of a series of N-methylamide embedded phases, prepared using supercritical carbon dioxide.

show abstract

Section: Alkyl Amide Polar-embedded Stationary Phasesmentioning

confidence: 98%

Polar-Embedded and Polar-Endcapped Stationary Phases for LC

2010

View full text Add to dashboard Cite

show abstract

“…Octadecyl stationary phases were prepared under solvent-free conditions, as described previously [6,33]. After silica gel modification, packings with high (C H 18 ) and low (C L 18 ) coverage density before and after end-capping (EC) were prepared.…”

Section: Reagents and Materialsmentioning

confidence: 99%

Effect of coverage density and structure of chemically bonded silica stationary phases on the separation of compounds with various properties

Buszewski¹,

Krupczyńska

Rychlicki

et al. 2006

J of Separation Science

View full text Add to dashboard Cite

The chemical character, geometry, and architecture of chemically formed surface layers determine interactions between stationary phase, analyte, and mobile phase, and therefore the retention mechanisms (partitioning, adsorption, ion exchange, steric exclusion) of separated analytes. These interactions also depend on the structure and chemical character of the solutes and the composition of the mobile phase. High-molecular-weight fullerenes (C60 and C70) and water-soluble selenium-containing peptides (833 and 2607 Da) were used for the evaluation of laboratory-prepared octadecyl stationary phases with high and low coverage density before and after end-capping. The aim of this work was to study differences in surface coverage density and homogeneity and conformational changes of chemically bonded moieties and the influence of these parameters on the separation of mixtures of selenopeptides and fullerenes with significantly different molecular masses. A topographical model of the chemically modified stationary surface is presented.

show abstract

“…Many authors demonstrated [188 192] that the selectivity of these bonded supports is different from the selectivity observed with conventional supports. These supports are often constituted of chemically bonded phases (both amino3-propyl and alkyl ligands) whose properties are modulated in function of the proportion of each ligand [193,194]. These supports are often constituted of chemically bonded phases (both amino3-propyl and alkyl ligands) whose properties are modulated in function of the proportion of each ligand [193,194].…”

Section: Electrostatic Shield Concept (Embedded Polar Group Stationarmentioning

confidence: 99%

Silica and other materials as supports in liquid chromatography. Chromatographic tests and their importance for evaluating these supports. Part I

et al. 2001

View full text Add to dashboard Cite

Reversed-phase liquid chromatography (RP-HPLC) has become a powerful and widely employed technique in the separation and analysis of a great variety of compounds with different functionalities. The most common type of stationary phase for RP-HPLC consists of nonpolar, hydrophobic organic species (e.g., octyl, octadecyl) attached by siloxane bonds to the surface of a silica support. In the first part of this article, a description of the many beneficial properties that make porous silica the most employed support in RP-HPLC will be presented, starting from the synthesis of silica. It is noteworthy that the chromatographic properties of the final column are strictly correlated to the preparation type. A silica surface possesses a number of attractive properties, but also some drawbacks. Unreacted or residual silanols interact with basic compounds and can induced peak tailing, which means a loss in chromatographic performance. This problem has lead many manufactures to produce stationary phases with reduced silanol activity which improve dramatically the peak shape of basic compounds. In the second part of this review, different approaches are proposed to obtain less reactive stationary phases

show abstract

Studies of physicochemical and chromatographic properties of mixed amino-alkylamide bonded phases

Cited by 56 publications

References 20 publications

Polar-Embedded and Polar-Endcapped Stationary Phases for LC

Polar-Embedded and Polar-Endcapped Stationary Phases for LC

Effect of coverage density and structure of chemically bonded silica stationary phases on the separation of compounds with various properties

Silica and other materials as supports in liquid chromatography. Chromatographic tests and their importance for evaluating these supports. Part I

Contact Info

Product

Resources

About