Studies of Protracted Shock in Guinea Pigs

Hahn, F.; Bernauer, W.

doi:10.1159/000230513

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1973

1978

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Cited by 4 publications

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“…The coronaries as well as the pul monary vessels react to antigen with a marked constriction [Giertz et al, 1961;Hahn and Bernauer, 1971], and this is probably responsible for cardiac failure, which is also observed in heart-lung prepa rations Hahn and Bernauer, 1969;Hahn et al, 1970].…”

Section: Introductionmentioning

confidence: 99%

Effect of Catecholamines and Sympatholytics on Survival and Circulatory Parameters in Protracted Anaphylactic Shock of Guinea Pigs

Molls¹,

Bernauer²

1976

Int Arch Allergy Immunol

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Protracted anaphylactic shock of guinea pigs led to death in over 90% of the animals, and good protection was obtained with an infusion of adrenaline after dibenamine pretreatment. Adrenaline alone, in doses which prevented the anaphylactic fall of arterial blood pressure, had no beneficial effect. Practolol abolished the therapeutic action of the combination of dibenamine/adrenaline. Stimulation of β-receptors by isoproterenol did not increase the survival rate. With dopamine, however, a significant prolongation of the survival times was obtained.

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Section: Introductionmentioning

confidence: 99%