The work is dedicated to study the production of the microcrystalline cellulose (MCC) from sunflower seed husks (SFH) by oxidation in an organic solvent, the dependence its hydromodule, yield and quality index of the MCC on the sunflower type. According to the morphological characteristics of SFH with different fat content, the effective hydromodulus of the MCC obtained from low-fat SFH is 1:12 g/ mL with a yield of 50.69%, while the effective hydromodulus for high-fat SFH is SFH:PAA 1:14 g/mL, it was determined that the yield will be equal to 43.49%. During the organic solvent oxidation, it was found that low fat sunflower husk undergoes delignification 3 times faster than high-fat, accordingly, the yield of cellulose and the content of β-cellulose are higher by 7.2% and 2.23%. That is, it became known that low-fat sunflower seed husk is an economically and ecologically effective raw materials in the production of the cellulosic materials.