Studies of the Clausius–Mossotti factor

Mortadi, A.; Melouky, A. El; Chahid, E. G; Moznine, Reddad El; Cherkaoui, O.

doi:10.30970/jps.20.4001

Cited by 12 publications

(14 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Electronic permanent dipolar, electrical conductivity, and interfacial mechanisms of polarization can contribute to the complex dielectric properties [ 11 , 32 ]. The real and imaginary parts of the Clausius–Mossotti factor are expressed as [ 33 ]:

…”

Section: Theoretical Backgroundmentioning

confidence: 99%

Signal-Based Methods in Dielectrophoresis for Cell and Particle Separation

et al. 2022

View full text Add to dashboard Cite

Separation and detection of cells and particles in a suspension are essential for various applications, including biomedical investigations and clinical diagnostics. Microfluidics realizes the miniaturization of analytical devices by controlling the motion of a small volume of fluids in microchannels and microchambers. Accordingly, microfluidic devices have been widely used in particle/cell manipulation processes. Different microfluidic methods for particle separation include dielectrophoretic, magnetic, optical, acoustic, hydrodynamic, and chemical techniques. Dielectrophoresis (DEP) is a method for manipulating polarizable particles’ trajectories in non-uniform electric fields using unique dielectric characteristics. It provides several advantages for dealing with neutral bioparticles owing to its sensitivity, selectivity, and noninvasive nature. This review provides a detailed study on the signal-based DEP methods that use the applied signal parameters, including frequency, amplitude, phase, and shape for cell/particle separation and manipulation. Rather than employing complex channels or time-consuming fabrication procedures, these methods realize sorting and detecting the cells/particles by modifying the signal parameters while using a relatively simple device. In addition, these methods can significantly impact clinical diagnostics by making low-cost and rapid separation possible. We conclude the review by discussing the technical and biological challenges of DEP techniques and providing future perspectives in this field.

show abstract

…”

Section: Theoretical Backgroundmentioning

confidence: 99%

Signal-Based Methods in Dielectrophoresis for Cell and Particle Separation

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Electronic permanent dipolar, electrical conductivity, and interfacial mechanisms of polarization can contribute to the complex dielectric properties [18,33]. The real and imaginary parts of the Clausius-Mossotti factor are expressed as [34]:…”

Section: Clausius-mossotti (Cm) Factormentioning

confidence: 99%

“…The first limit for the real part is regarded at low frequencies and creates an ionic contribution to the conductivity [34]:…”

Section: Clausius-mossotti (Cm) Factormentioning

confidence: 99%

“…It is simple to verify that this limit can be positive if > or negative if < . Another limit is considered at higher frequencies, giving the ionic contribution to the permittivity [34]:…”

Section: Clausius-mossotti (Cm) Factormentioning

confidence: 99%

“…Moreover, this situation can be used for particle separation in a mixture in which the condition = for each different particle happens at a different frequency [35]. It is possible to detect the crossover frequency ( ) for which fCM is zero and DEP goes from a positive to negative situation or vice versa [34]:…”

Section: Clausius-mossotti (Cm) Factormentioning

confidence: 99%

See 2 more Smart Citations

Signal-Based Methods in Dielectrophoresis for Cell Separation

Farasat¹,

Ronizi²,

Bakhshi³

et al. 2022

Preprint

View full text Add to dashboard Cite

Separation and detection of cells and particles in a suspension are essential for various applications, including biomedical investigations and clinical diagnostics. Microfluidics realizes the miniaturization of analytical devices by controlling the motion of a small volume of fluids in microchannels and microchambers. Accordingly, microfluidic devices have been widely used in particle/ cell manipulation processes. Different microfluidic methods for particle separation include dielectrophoretic, magnetic, optical, acoustic, hydrodynamic, and chemical techniques. Dielectrophoresis (DEP) is a method for manipulating polarizable particles’ trajectories in non-uniform electric fields using unique dielectric characteristics. It provides several advantages for dealing with neutral bioparticles owing to its sensitivity, selectivity, and noninvasive nature. This review provides a detailed study on the signal-based DEP methods that use the applied signal parameters, including frequency, amplitude, phase, and shape for cell/particle separation and manipulation. Rather than employing complex channels or time-consuming fabrication procedures, these methods realize sorting and detecting the cells/particles by modifying the signal parameters while using a simple device. In addition, these methods can significantly impact clinical diagnostics by making low-cost and rapid separation possible.

show abstract

When to Use Rectangular Waveforms in Dielectrophoresis Application to Increase Separation and Sorting Efficiency

Boldt,

Weirauch,

Späth

et al. 2024

Electrophoresis

View full text Add to dashboard Cite

In this study, the influence of using rectangular waveforms is comprehensively investigated on the separation and sorting efficiency of dielectrophoretic (DEP) processes. Besides positive effects on DEP experiments, cases of a diminished force due to rectangular waveforms are investigated and discussed. This investigation encompasses two primary experimental setups. First, microparticle‐focusing experiments are carried out using a pair of electrodes within a microfluidic channel. Second, separation experiments are performed using a macroscopic insulator‐based dielectrophoretic filter. The study reveals that harmonics of rectangular signals can have a positive impact on separation or sorting efficiency when compared to sinusoidal waveforms, provided that these harmonics contribute to the overall DEP force with the same sign. This positive effect is found to depend on the ratio between the applied fundamental frequency and the cross‐over frequency in the Clausius–Mossotti factor. However, violating related derived boundary conditions leads to negative effects and a decrease in the DEP net force.

show abstract

Studies of the Clausius–Mossotti factor

Cited by 12 publications

References 4 publications

Signal-Based Methods in Dielectrophoresis for Cell and Particle Separation

Signal-Based Methods in Dielectrophoresis for Cell and Particle Separation

Signal-Based Methods in Dielectrophoresis for Cell Separation

When to Use Rectangular Waveforms in Dielectrophoresis Application to Increase Separation and Sorting Efficiency

Contact Info

Product

Resources

About