Studies of the Effect of 2-Mercaptoethanol on Swine Anti-Sera against Japanese Encephalitis Virus I.

Otsuka, Shuzo; Manako, Kenji; Mori, Ryoichi; Kunihiro, Hidefumi; Motomura, Ichiro

doi:10.3412/jsb.21.724

Japanese journal of bacteriology

1966

DOI: 10.3412/jsb.21.724

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Studies of the Effect of 2-Mercaptoethanol on Swine Anti-Sera against Japanese Encephalitis Virus I.

Shuzo Otsuka¹,

Kenji Manako²,

Ryoichi Mori³

et al.

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Response of Erythrocebus patas monkeys to experimental infection with the orbivirus Orungo virus

Tomori

1978

Transactions of the Royal Society of Tropical Medicine and Hygi

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The response of Erythrocebus patas monkeys experimentally inoculated by the intravenous and subcutaneous routes with Orungo virus (family Reoviridae, genus Orbivirus) was studied with reference to development of clinical signs, circulation of virus and antibody response. None of the animals showed clinical disease nor did they circulate virus. However, all the animals developed complement fixing (CF), neutralizing (N) and agar gel (AG) precipitating antibodies between day seven and day 14 post infection (p.i.). The CF antibodies appeared earlier and lasted for a longer period than did the N antibodies. The presence of transient 2-mercaptoethanol (2-ME) sensitive CF antibodies was demonstrated in sera collected between day seven and day 14 p.i. The significance of these findings in the interpretation of serological surveys in man for Orungo virus antibody is discussed.

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Response of Erythrocebus patas monkeys to experimental infection with the orbivirus Orungo virus

Tomori

1978

Transactions of the Royal Society of Tropical Medicine and Hygi

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Seroepizootiology of Bovine Japanese Encephalitis in Two Prefectures

Sakai

Horimoto

Ishizaki

et al. 1991

JAPAN JOURNAL OF VETERINARY INFORMATICS

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From August to December 1987, 937 sera from dairy cows in Saitama and Aichi Prefectures were tested for hemagglutination inhibition (HI) antibody to Japanese encephalitis virus (JEV). Monthly positivity rates as well as antibody titers were the highest in September and the lowest in December.Nineteen of 79(24%) from Saitama and 12 to 14(86%) from Aichi showing antibody titers of 1:40 or higher were suggested to have been very secently infected becouse of 2-mercaptoethonol (2ME) sensitivety of antiblody.

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Studies of the Effect of 2-Mercaptoethanol on Swine Anti-Sera against Japanese Encephalitis Virus I.

Cited by 2 publications

References 0 publications

Response of Erythrocebus patas monkeys to experimental infection with the orbivirus Orungo virus

Response of Erythrocebus patas monkeys to experimental infection with the orbivirus Orungo virus

Seroepizootiology of Bovine Japanese Encephalitis in Two Prefectures

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