Studies of the Essential Oil Composition, Antibacterial and Antifungal Activity Profiles of<i>Frankenia laevis</i>L. from Tunisia

Mahjoub, Mohamed Ali; Mighri, Zine; Chriaa, Jihane; Daami, Majda; Saïdana, Dhouha; Helal, Ahmed Noureddine

doi:10.1080/10412905.2010.9700343

Cited by 6 publications

(22 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Frankenia laevis is a halophyte that has been widely recognized for its prominent antimicrobial effects, namely as antibacterial against both Gram-positive (S. aureus, S. epidermidis and Micrococcus luteus) and Gram-negative (E. coli and Salmonella typhimurium) bacteria (Saïdana et al, 2010). Interestingly to highlight is that this significant potential is reached by using both the aerial plant parts extract and essential oils (Jdey et al, 2017;Mahjoub et al, 2010).…”

Section: Health Effectsmentioning

confidence: 99%

Halophytic herbs of the Mediterranean basin: An alternative approach to health

Petropoulos

Karkanis

Martins

et al. 2018

Food and Chemical Toxicology

View full text Add to dashboard Cite

Wild native species are usually grown under severe and stressful conditions, while a special category includes halophytic species that are tolerant to high salinity levels. Native halophytes are valuable sources of bioactive molecules whose content is higher in saline than normal conditions, since the adaptation to salinity mechanisms involve apart from changes in physiological functions the biosynthesis of protectant molecules. These compounds include secondary metabolites with several beneficial health effects which have been known since ancient times and used for medicinal purposes. Recent trends in pharmaceutical industry suggest the use of natural compounds as alternative to synthetic ones, with native herbs being strong candidates for this purpose due to their increased and variable content in health promoting compounds. In this review, an introductory section about the importance of native herbs and halophyte species for traditional and modern medicine will be presented. A list of the most important halophytes of the Mediterranean basin will follow, with special focus on their chemical composition and their reported by clinical and ethnopharmacological studies health effects. The review concludes by suggesting future requirements and perspectives for further exploitation of these valuable species within the context of sustainability and climate change.

show abstract

Section: Health Effectsmentioning

confidence: 99%

Halophytic herbs of the Mediterranean basin: An alternative approach to health

Petropoulos

Karkanis

Martins

et al. 2018

Food and Chemical Toxicology

View full text Add to dashboard Cite

show abstract

“…These compounds not only perform critical functions in plant fitness (e.g., as plant growth regulators, defensive compounds, pollinator attractants) but also are extensively used as preservatives and flavor enhancers, analgesics, antiseptics, chemotherapeutics, and feed stocks for chemical syntheses (1)(2)(3)(4)(5). Despite its simple structure and widespread distribution, full understanding of the biochemical pathways leading to BA formation remains incomplete.…”

mentioning

confidence: 99%

Completion of the core β-oxidative pathway of benzoic acid biosynthesis in plants

Qualley¹,

Widhalm²,

Adebesin

et al. 2012

Proc. Natl. Acad. Sci. U.S.A.

168

136

View full text Add to dashboard Cite

Despite the importance of benzoic acid (BA) as a precursor for a wide array of primary and secondary metabolites, its biosynthesis in plants has not been fully elucidated. BA formation from phenylalanine requires shortening of the C 3 side chain by two carbon units, which can occur by a non–β-oxidative route and/or a β-oxidative pathway analogous to the catabolism of fatty acids. Enzymes responsible for the first and last reactions of the core BA β-oxidative pathway (cinnamic acid → cinnamoyl-CoA → 3-hydroxy-3-phenylpropanoyl-CoA → 3-oxo-3-phenylpropanoyl-CoA → BA-CoA) have previously been characterized in petunia, a plant with flowers rich in phenylpropanoid/benzenoid volatile compounds. Using a functional genomics approach, we have identified a petunia gene encoding cinnamoyl-CoA hydratase-dehydrogenase ( PhCHD ), a bifunctional peroxisomal enzyme responsible for two consecutively occurring unexplored intermediate steps in the core BA β-oxidative pathway. PhCHD spatially, developmentally, and temporally coexpresses with known genes in the BA β-oxidative pathway, and correlates with emission of benzenoid volatiles. Kinetic analysis of recombinant PhCHD revealed it most efficiently converts cinnamoyl-CoA to 3-oxo-3-phenylpropanoyl-CoA, thus forming the substrate for the final step in the pathway. Down-regulation of PhCHD expression in petunia flowers resulted in reduced CHD enzyme activity, as well as decreased formation of BA-CoA, BA and their derived volatiles. Moreover, transgenic lines accumulated the PhCHD substrate cinnamoyl-CoA and the upstream pathway intermediate cinnamic acid. Discovery of PhCHD completes the elucidation of the core BA β-oxidative route in plants, and together with the previously characterized CoA-ligase and thiolase enzymes, provides evidence that the whole pathway occurs in peroxisomes.

show abstract

“…Nerolidol ( 116 ) and farnesyl acetate ( 119 ) were the most widespread sesquiterpenes present in F. laevis [ 43 ]. Furthermore, β-caryophyllene ( 135 ) was the major compound detected in F. pulverulenta .…”

Section: Phytochemical Profile Of Frankenia Plantsmentioning

confidence: 99%

Phytochemical Profiles and Biological Activities of Frankenia Species: A Review

Khaled,

Ouache,

Pale

et al. 2024

Molecules

View full text Add to dashboard Cite

The relatively small Frankeniaceae family is represented by halophyte plants, growing in arid and semi-arid climates in saline, alkaline or calcareous soils. Due to their living conditions, they usually produce a large diversity of compounds, which often exhibit bioactivities. Some species of this genus have long been used as traditional herbal medicines to treat dysentery, diarrhea, gonorrhea, vaginal leucorrhea, respiratory diseases and wounds. To date, several studies on either phytochemical or pharmacological aspects, or both, have revealed that this genus is a rich source of diverse and novel bioactive chemicals, including phenolics, flavonoids, alkaloids and fatty acids. This review describes all the reported chemical profiles of Frankenia species, as well as the corresponding biological properties, when available. The aim of this review is to show the potential of these plants for various applications, especially therapeutic ones.

show abstract

Studies of the Essential Oil Composition, Antibacterial and Antifungal Activity Profiles ofFrankenia laevisL. from Tunisia

Cited by 6 publications

References 23 publications

Halophytic herbs of the Mediterranean basin: An alternative approach to health

Halophytic herbs of the Mediterranean basin: An alternative approach to health

Completion of the core β-oxidative pathway of benzoic acid biosynthesis in plants

Phytochemical Profiles and Biological Activities of Frankenia Species: A Review

Contact Info

Product

Resources

About