This paper aims to analyze effective approaches to waste management in agro-industrial cluster. It considers the studies confirming the relevance and importance of the development of technologies for processing and recycling of waste from the agro-industrial cluster, and, in particular, waste from pig farms. The methods of system analysis, information synthesis, statistical data analysis were used to identify the existing problems. The period from 2000 to 2020 was considered. The most popular directions and production branches have been identified. Quantitative analysis of scientific works on recycling and disposal of waste of agro-industrial cluster was carried out. Based on the data obtained, graphs were built, comparisons were made, conclusions were drawn about the demand for the development of resource-saving technologies, and waste recycling. Based on the analysis of the existing approaches, the authors proposed a cluster form of organization and waste management.