Studies of the interaction of 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) with imidazole in acetonitrile

Dworniczak, M.

doi:10.1007/bf02096699

Cited by 6 publications

(1 citation statement)

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“…7). These absorption bands are characteristic for the absorption of the radical anion DDQ −• [4,8,42,43]. The observed enhanced absorption band intensities, immediately after mixing D and A, supports the fact that the CT complex formed is of the dative-type structure, which consequently converts to an ionic intermediate possessing the spectral characteristics of radical anion [23].…”

Section: Interaction Of Pantoprazole With Ddqsupporting

confidence: 63%

Spectroscopic studies on the dynamics of charge‐transfer interaction of pantoprazole drug with DDQ and iodine

Pandeeswaran

El‐Mossalamy

Elango

2009

Int J of Chemical Kinetics

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Spectrophotometric method was used to study the kinetics of charge-transfer (CT) complexes of pantoprazole with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and iodine. The reactions of DDQ and iodine with pantoprazole have been investigated in different solvents at three different temperatures. The products of the interactions have been isolated and characterized using UV-vis, GC-MS, FT-IR, and far-IR spectral techniques. The rate of formation of the product has been measured and discussed as a function of solvents and temperature. The iodine complex indicates the formation of the tri-iodide CT complex with a general formula [(PTZ)I] + I − 3 . The characteristic strong absorptions of I − 3 are observed around 360 and 290 nm in the electronic spectra, and the far-IR spectrum exhibits three characteristic vibrations of I − 3 unit at 156, 112, and 69 cm −1 assigned to ν as (I-I), ν s (I-I), and δ(I − 3 ), respectively. The activation parameters ( G # , S # , and H # ) were obtained from the temperature dependence of the rate constants. The influence of relative permittivity of the medium on the rate indicated that the intermediate is more polar than the reactants, and this observation was further well supported by spectral studies. Based on the spectrokinetic results, plausible mechanisms for the interaction of the drug with the chosen acceptors, which proceed via the formation of CT complexes and its transformation into final products, have been proposed.

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