Studies of the Rate of Transfer of D&lt;SUB&gt;2&lt;/SUB&gt;O Across the Pericardium of Dogs

Takashina, T; Cronvich, J. A.; Burch, George E.

doi:10.1253/jcj.25.757

Cited by 2 publications

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“…About 20% of radioactive albumin injected into the pericardial cavity can be recovered from the pleura] cavities, two hours after the injection (3). In vitro studies by Takashina et al (6,7) showed that the pericardium was highly permeable to water. Their estimates of the potential daily unidirectional transfer of water across the canine pericardium, however were inconsistent with the time course of pericardial fluid diasppearance in the intact animal (1,8).…”

Section: Discussionmentioning

confidence: 99%

Hydraulic permeability of canine and human pericardium in vitro

1980

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SummaryThe purpose of the present study was to determine the hydraulic conductance (Lp) of human and canine pericardium and evaluate the influence of several factors on Lp. The Lp of canine and human pericardium was 9.6 • 10 -5 and 4.5 • 10 -5 ml/ min/cm2/crnH20 respectively. There was no relationship between Lp and membrane thickness within each species but membrane thickness differences between species may account for some of difference in Lp. Hypertonic media cause Lp to increase. Lp was independent of hydraulic pressure over the range from 6 to 15 cm H20. The magnitude of Lp suggest that the parietal pericardium is a potentially important route for removal of pericardial fluid especially in cardiac tamponade.

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Section: Discussionmentioning

confidence: 99%

Hydraulic permeability of canine and human pericardium in vitro

1980

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“…Both active and passive mechanisms of formation have been proposed, though the evidence to support either hypothesis is inconclusive (Takashina, Cronvitch & Burch, 1961;Holt, 1970).…”

Section: Introductionmentioning

confidence: 99%

“…Few observations have been made on the composition of pericardial fluid and little is known of the means by which it is formed and drained. Both active and passive mechanisms of formation have been proposed, though the evidence to support either hypothesis is inconclusive (Takashina, Cronvitch & Burch, 1961;Holt, 1970).…”

Section: Introductionmentioning

confidence: 99%

A study of the composition of pericardial fluid, with special reference to the probable mechanism of fluid formation.

Gibson¹,

Segal²

1978

The Journal of Physiology

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SUMMARYThe composition of pericardial fluid and simultaneously withdrawn plasma have been measured in rabbits and greyhounds.1. Sodium and chloride distributions were found to be not markedly different from the ratio predicted for a passive distribution. The small deviation found in greyhounds could be largely corrected by the in vitro dialysis of plasma against pericardial fluid.2. Calcium and magnesium were distributed in a manner expected from a passive ultrafiltrate of plasma.3. Pericardial fluid was found to contain between one quarter and one third of the protein of plasma.4. Separation of the protein constituents demonstrated a far higher proportion of albumin to other proteins in the pericardial fluid.5. The osmolality of plasma was slightly higher than that of pericardial fluid, as would be expected from a plasma ultrafiltrate.6. The potassium concentration of pericardial fluid was higher than the plasma concentration in all animals studied. This difference could be abolished, and an expected distribution obtained in the samples from greyhounds, by the in vitro dialysis of plasma against pericardial fluid. This observation for potassium cannot be attributed to haemolysis of blood in pericardial fluid samples or to the use of any inappropriate references. It is suggested that the elevated potassium concentration of pericardial fluid may reflect the lability of the cardiac intracellular potassium during cardiac contraction.7. The results obtained in this study do not support the concept of an active secretion of pericardial fluid as has been claimed by others. The distribution of ions would appear to be passive and to follow the values predicted by the Gibbs-Donnan relationship.

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Studies of the Rate of Transfer of D<SUB>2</SUB>O Across the Pericardium of Dogs

Cited by 2 publications

References 0 publications

Hydraulic permeability of canine and human pericardium in vitro

Hydraulic permeability of canine and human pericardium in vitro

A study of the composition of pericardial fluid, with special reference to the probable mechanism of fluid formation.

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