Studies on Analgesics of Aniline Series. I. Preparation and Properties of β-Alaninamide Series

Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles

“…N,N-Dimethyl-3-phenylamino-propionamide ( 3a ): The product was obtained as a white solid in a yield of 74% (0.34 g), MP: 103–106 °C [30]. 1 HNMR (600 MHz, CDCl 3 ) δ 7.17 (dd, J = 8.4, 7.4 Hz, 2H), 6.69 (t, J = 7.3 Hz, 1H), 6.64 (d, J = 7.7 Hz, 2H), 4.33 (s, 1H), 3.48 (t, J = 6.0 Hz, 2H), 2.95 (d, J = 3.5 Hz, 6H), 2.59 (t, J = 6.0 Hz, 2H).…”