Studies on Antitumor Activities and Antitumor Principles of Chinese Herbs. I. Antitumor Activities of Chinese Herbs

The Cytotoxic Saponin from Heat-Processed Achyranthes fauriei Roots

“…1), a triterpenoid saponin which was reported to be a cytotoxic saponin previously. 6,12) IC 50 value of chikusetsusaponin IVa against SK-Hep-1 cells was 18.9 mg/ml and it was comparable to that of cisplatin (IC 50 ϭ12.7 mg/ml).…”

Chemical Constituents and Toxicity of Essential Oils of Oriental Arborvitae, Platycladus orientalis (L.) Franco, against Three Stored-Product Beetles

“…The test revealed increased neonate larval mortality (Papachristos and Stamopoulos, 2002). The oils has also shown antimicrobial and fungitoxic properties (Hassanzadeh et al, 2001;Guleria et al, 2008) and antitumoral, cytotoxic, and antioxidant effects (Kosuge et al, 1985;Emami et al, 2005;Emami et al, 2011a;2011b Extracts of P. orientalis have been shown to possess a range of biological activities, including insecticidal action against larvae of malaria and Japanese encephalitis vector (Sharma et al, 2005), control of Potato leaf roll virus (PLRV) in potato plants (Al-Ani et al, 2010), antioxidant effects (Nizam and Mushfiq, 2007), and antifungal activity (Alinezhad et al, 2011). The molluscicidal activity of extracts and leaf powder of P. orientalis was studied against the snail Lymnaea acuminata (Lamarck) (Singh and Singh, 2009).…”

Eclipta alba (L.) An Ethnomedicinal Herb Plant, Traditionally Use in Ayurveda

“…The compounds Wedelolactone, apigenin, and luteolin extracted from A. alba have been phytochemically analyzed a dose dependent Hepatitis C virus inhibition and Anti-HCV replication activity in cell culture system [1]. Wedelolactone has been reported to have the property used for treating hepatitis and cirrhosis [2], as antibacterial, and antihemorrhagic [3]. Petroleum ether and ethanol extract of Eclipta alba have reduced hair growth time by about 50% tested in albino rats (Table 1) [4].…”