Studies on Drug Sensitivity and Bacterial Prevalence of UTI in Tribal Population of Paschim Medinipur, West Bengal, India

Abstract

The result will be very much helpful for medical practitioners and clinicians of the region to create a common database for UTI causing microorganisms and their antibiogram profile. Background:There is paucity of information in regards to prevalence of bacteria in urinary tract infection (UTI) in tribal population. Objectives: This study was conducted to observe dominant organisms causing UTI in tribal community of Medinipur, West Bengal, India and evaluate their sensitivity to common antibiotics. Patients and Methods: A total number of 4,416 urine samples of clinically suspected UTI attending outpatient department and hospitalized tribal patients of West Medinipur zone were collected. Urine samples were inoculated on Blood agar, MacConkey's agar, and cystine lactose electrolyte deficient (CLED) agar and incubated at 37 o C for 24 hr and extended up to 48 hr in cases of negative growth. Antibiotic susceptibility testing against the most common causative bacteria was also performed. (1.76%). E.coli was the most common pathogen of UTI in tribal population with female susceptibility predominantly more than male patients. Among16 antibiotics, amikacin (14.30%) and meropenem (12.0%) were shown to be the most sensitive to and Tobramycin (0.66%) the least effective on E.coli. Conclusions: Females are more susceptible to UTI than males and the most effective drug (sensitive against isolated E. coli) is Amikacin. Therefore, culture and antimicrobial drug sensitivity testing are essential procedures for proper management of UTI in tribal population.

Bacterial Profile, Antibiotic Susceptibility Pattern and Associated Factors Among Patients Attending Adult OPD at Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia

“…The other isolate which was identified in this study was Pseudomonas aeruginosa with a proportion of (12.6%), this result was close to studies conducted in Metu, Ethiopia (10.35) 45 and Harar, Ethiopia (10%). 37 But it was higher than different studies in India (4.53%), 46 Nigeria (4.4%), 43 Harar Ethiopia (6.4%), 42 Harar, Ethiopia (3.1%), 24 Addis Ababa, Ethiopia (1.2%) 33 and Hawassa, Ethiopia (3.0%). 47 In this study the proportion of CoNS was (11.8%) this result is closer to two studies previously conducted in Harar, Ethiopia (7.9%) and (8.2%), 24,42 this result is higher than a study conducted in India (2.7%).…”

RETRACTED ARTICLE: Profile of Virulence Factors in the Multi-Drug Resistant Pseudomonas aeruginosa Strains of Human Urinary Tract Infections (UTI)

“…Comparable findings have been described by Zorc et al ( 17 ), Bitsori et al ( 5 ), and Nickavar and Sotoudeh ( 15 ). Several investigations that were conducted on UTIs caused by P. aeruginosa in India ( 16 ), Iran ( 18 , 19 ), Kolkata ( 20 ), and Nigeria ( 21 ) revealed that the total prevalence of bacteria is about 3 - 16% which was considerable. Differences in the type of UTIs, method of sampling, number of samples collected, method of experiment, sex and age of patients, and the geographical area where the samples were collected are the main contributing factors for the differences in the prevalence of P. aeruginosa in various investigations.…”

Urinary pathogenic bacterial profile, antibiogram of isolates and associated risk factors among pregnant women in Ambo town, Central Ethiopia: a cross-sectional study

“…Diagnosis of UTI is defined on the basis of significant colony count of ≥10 5  cfu/ml for Gram-negative and Gram-positive bacteria [7]. Growths on the culture media were identified by using bacterial growth characteristics (morphology), Gram staining [19, 20] and general biochemical tests [21, 22]. …”